RESUMO
A study was carried out on 76 patients attending outpatients' department of medicine, Government Medical College, Nagpur. These patients had either (a) atypical angina or (b) no symptoms but certain factors for ischaemic heart disease. All cases were subjected to maximal stress test. Thirty-five cases (46.05%) showed a positive result on the basis of 'ST' segment depression of 2 mm or more. In the absence of facilities for coronary angiography, treadmill test is an important diagnostic tool for ischaemic heart disease.
Assuntos
Adulto , Angiografia Coronária/métodos , Diagnóstico Diferencial , Teste de Esforço/métodos , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Isquemia Miocárdica/diagnóstico , Fatores de RiscoRESUMO
We studied the effect of atenolol 100 mg/day in 50 symptomatic patients of mitral stenosis and normal sinus rhythm, in a placebo controlled study. Atenolol caused significant bradycardia as compared to placebo (vitamin C; P < 0.001) without any adverse effects. It also increased exercise capacity significantly as compared to placebo (P < 0.001). All the patients were followed up to the period of 9 months and no adverse effects were seen. We conclude that beta adrenergic blocking drugs like atenolol can be used as the only treatment for patients with mitral stenosis without congestive heart failure and in sinus rhythm, for long-term symptomatic relief.
Assuntos
Adolescente , Adulto , Atenolol/uso terapêutico , Feminino , Frequência Cardíaca/fisiologia , Humanos , Masculino , Pessoa de Meia-Idade , Estenose da Valva Mitral/tratamento farmacológico , Valores de Referência , Fatores de TempoAssuntos
Ampicilina/uso terapêutico , Resistência a Ampicilina , Cloranfenicol/uso terapêutico , Resistência ao Cloranfenicol , Países em Desenvolvimento , Surtos de Doenças , Resistência Microbiana a Medicamentos , Humanos , Índia/epidemiologia , Salmonella typhi/efeitos dos fármacos , Combinação Trimetoprima e Sulfametoxazol/uso terapêutico , Febre Tifoide/tratamento farmacológicoRESUMO
S. typhi was isolated from 241 patients of pyrexia between July 1990 and March 1991. Multiple drug resistance was observed in 220 (91.3%) strains, the commonest pattern of drug resistance being ACCoT (49.4%). Predominance of phage type E1 in 196 (81.3%) strains and biotype I in 225 (93.4%) strains was observed. All ACCoT strains belonged to phage type E1 and all strains of phage type E1 belonged to biotype I.