RESUMO
Background: Panchavalkala Choorna is a poly herbal compound made from the barks of five major drugs from the Ficus family. It is widely quoted as an effective remedy in various skin disorders explained under the wide spectrum of Kushta (skin disorders), mentioned in Ayurvedic classics. However, till date no published data is available on the analytical profile of this compound formulation. The present study was aimed to standardize and develop the pharmacognostical and phytochemical profile of Panchavalkala Choorna. The compund was prepared as per classical methods and analytical findings were systematically recorded. The samples were subjected to organoleptic analysis, physicochemical analysis and High performance Thin Layer Chromatography (HPTLC) examination by optimizing the solvent systems. Pharmacognostical profile of Panchavalkala Choorna was established. Loss on drying, Specific gravity, Viscosity and Refractive index, Iodine value, Acid value and Saponification value of Panchavalkala Choorna were found within prescribed limits. HPTLC fingerprinting profile of ST revealed 6 spots at 254 nm and 4 spots at 366 nm. Two spots were merging in both the long and short UV, showing common characters in both the wavelengths.
RESUMO
Ayurveda classified the drugs in various ways and one of which the classification is based on Rasa (taste) dominancy. Rasa is essential to identify drugs and to know its therapeutic application. In this study the drug has been selected according to Charaka classification of Tikta Rasa (bitter taste) drugs with an aim to find out the similar characters among all the drugs having bitter Rasa dominancy. Till date there is no data available regarding the pharmacognostical evaluation in concern bitter taste. For the first time selected five bitter drugs are subjected to various pharmacognostical evaluation, result reveals that Organoleptic characters of all five drugs give bitter taste, microscopic evaluation revealed that presence of starch grain, vessels, fiber , brown content are dominant in all five raw drug and all the five powder subjected to alkaloid test by using dragondroff reagent and give positive result for alkaloids.