RESUMO
OBJECTIVE: The present study was designed to evaluate the prophylactic efficacy after the correction of dentofacial deformities between short- and long-term penicillin and amoxicillin-clavulanic acid. MATERIAL AND METHOD: The present study was prospective, randomized, and double blinded. Patients were separated into four groups randomly: short-term and long-term (5 days) penicillin and short-term and long-term (5 days) amoxicillin-clavulanic acid. RESULTS: One hundred twenty two patients were assigned randomly into the four groups. Infection developed in a patient in the short-term amoxicillin-clavulanic acid group and in a patient in the long-term penicillin group. CONCLUSION: There were no differences in infection between the two groups of antibiotics. Based on the present study, short-term penicillin is still the most appropriate choice for prophylactic antibiotic in orthognathic surgery.
Assuntos
Adolescente , Adulto , Combinação Amoxicilina e Clavulanato de Potássio/uso terapêutico , Antibacterianos/uso terapêutico , Antibioticoprofilaxia , Infecções Bacterianas/prevenção & controle , Método Duplo-Cego , Quimioterapia Combinada , Feminino , Humanos , Masculino , Osteotomia/métodos , Penicilinas/uso terapêutico , Complicações Pós-Operatórias , Cuidados Pré-Operatórios , Prognatismo/cirurgia , Estudos Prospectivos , Articulação Temporomandibular/cirurgia , Adulto JovemRESUMO
The oral assessments and oral care prior to cancer treatment are important to eliminate predisposing factors of oral complications from cancer therapy. Meticulous maintenance of oral hygiene and topical fluoride application are essential in the prevention and management of oral complications. Palliative and conservative treatments are the treatment of choice for oral complications. Periodically oral assessments and care should be performed after cancer treatment for the early detection and interventions of any treatment complications.