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1.
Artigo | IMSEAR | ID: sea-209346

RESUMO

Introduction: In the electrocardiogram, the QT interval reflects the duration of depolarization and repolarization of the ventricularmyocardium thus reflects changes in local myocardial milieu. Dispersion of repolarization is thought to reflect regional heterogeneityof the recovery process within the myocardium, which believed to be important in the genesis of ventricular arrhythmias.Purpose of Study: The purpose of the present study was to predict the risk of life-threatening ventricular arrhythmias andother cardiac complications after acute ST-elevation myocardial infarction (STEMI) event with using rate adjusted corrected QT(QTc) dispersion as one of the cheapest modalities and non-invasive investigation, which may reflect as a prognostic marker.Materials and Methods: The present study had been carried out in the Department of Medicine, NSCB. Medical College andassociated Hospital, Jabalpur, Madhya Pradesh, India, from March 2017 to August 2018. This was a case–control prospectiveobservational study. The targeted populations were 60 cases of both sexes with the age group of ≥18–≤70 years, and age- andsex-matched 60 apparently healthy control subjects.Results: Mean QTc dispersion was increased in patients of acute MI compared to control subjects; which were found statisticallyhighly significant. The mean QTc dispersion remained consistently high in a group of patients with cardiac complications incomparison to patients without cardiac complications on day 1 up to discharge. The mean QTc dispersion was found high inpatients who were died compared to who were survived on day 1.Conclusion: It could be concluded that QTc dispersion measurement may provide a potentially simple, cheap, and non-invasivemethod of identification of patients with acute MI (STEMI) at risk of development of ventricular arrhythmias and also relates tothe prognosis in that patients and the future may prove to be an independent predictor of death.

2.
Artigo em Inglês | IMSEAR | ID: sea-177927

RESUMO

Behçet’s syndrome (BS) or Behcet’s disease (BD) is a chronic multisystem disorder of unknown etiology that is characterized mainly by recurrent mucocutaneous, articular, neurological, gastrointestinal, and ophthalmological lesions. A 20-year-old unmarried, Hindu, male patient presented with a history of recurrent oral and genital ulcers, large joint infl ammatory oligoarthritis predominantly in right knee joint, folliculitis (dermatographia) on the legs, epididymitis, acneiform lesions over face, and panuveitis with associated constitutional symptoms. His Laboratory examinations were nonrevealing except for a moderate rise in erythrocyte sedimentation rate and C-reactive protein. Th is patient meets, in 1990, the International Study Group criteria for BD/BS. Th e main clinical manifestations of this disease are discussed and its early recognition and treatment response is emphasized.

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