RESUMO
Objective: To find out the presence or absence of insulin resistance syndrome [lRS] in type-2 diabetes mellitus patients
Material and Methods: The study included 55 TZDM patients [34 male and 21 female], who were already taking oral anti diabetic drugs for the last 3 - 5 years. Obesity or weight gain in TZDM patients aggravates metabolic disturbances along with increased insulin resistance. The five variables in TZDM patients were studied as per recommendations of the United States National Cholesterol Education Program Adult Treatment Panel-Ill [ATP-Ill], to find out the presence or absence of insulin resistance syndrome [IRS] in TZDM patients. The TZDM patients who had shown the presence of three or more variables out of five 2 were considered to have IRS
Results: 32 [58.18%] TZDM patients [20 male and 12 female] had IRS. The T2DM patients with lRS had significant [p<0.001] increase in mean blood glucose levels, waist circumference, triglyceride levels and in systolic and diastolic blood pressure. The mean HDL Cholesterol was significantly [p<0.001] decreased in TZDM patients with IRS as compared to TZDM patients without IRS
Conclusion: An increase in waist circumference in TZDM patients will increase the prevalence of insulin resistance syndrome