Histopathological Spectrum Of Polypoidal Lesions Of Nasal & Para-Nasal Sinuses

The nasal cavity, para-nasal sinuses and nasopharynx form a functional unity that is reflected in the communality of the pathologic processes that involve the region. This is particularly the case for the first two components, which are often grouped under the term sinonasal. The two main types of epithelia lining these structures are stratified squamous and respiratory type pseudo-stratified columnar1. A wide array of neoplastic and non-neoplastic conditions present as a mass lesion2. Nasal polyps are polypoidal masses arising from mucus membranes of nose and para-nasal sinuses and are one of the most commonly encountered lesions in clinical practice3. The formation of nasal polyps is associated with recurrent attacks of rhinitis. They are focal protrusions of the mucosa which may reach 3-4 centimetres in length4. They are often bilateral and multiple, which lead to visible broadening of nose. These lesions affect males predominantly in 3:1 ratio1. Histopathological analysis helps to distinguish the nature of these lesions and thereby its management and prognostication.

Clinico-Histopathological Analysis In Patients With Abnormal Uterine Bleeding.

Background: Menstrual disturbance is one of the commonest gynecological problems for the curettage or hysterectomy specimen received by pathologist. During reproductive age group, approximately 9-30% of women suffer from menorrhagia or abnormal uterine bleeding & the incidence increases as age advances. Being most common gynecological problem, present study is aimed to know full spectrum of AUB and its pathological aspects. Methods: 200 cases were taken from NHL Municipal Medical College, Ahmedabad over a period of 3 years. Clinical history and radiological findings of cases of abnormal uterine bleeding were noted. Histopathological analysis was done. Data were analyzed and correlation between clinical and histopathological findings were studied. Results: Maximum numbers of patients were in 41-50 years (41.5%) of age group and next are in 31-40 years (38%) of age group. Proliferative pattern (24%) was most common pattern in non-structural causes of AUB and Leiomyoma (22.5%) was the most common structural cause of AUB. Pregnancy related causes of AUB were common in less than 40 years of age group. Malignancy was more common in more than 50 years of age group. Atrophic endometrium (33.33%) was the most common cause of post-menopausal bleeding. Conclusion: Endometrial specimen examination by histopathological evaluation is gold standard procedure to know the exact pathology for AUB and for further management of patients.[Falguni S NJIRM 2016; 7(5):14-17]

An unusual presentation of myxoid liposarcoma: a case report.

A 50 year old female had a myxoid liposarcoma of left thigh that was widely excised. After three years, she presented with a soft tissue mass in right hypochondriac region, which was diagnosed as myxoid liposarcoma on fine needle aspiration cytology (FNAC) and was confirmed histologically.

Follow up of survival and quality of life in children after intensive care.

OBJECTIVE:To evaluate the health related quality of life of children after intensive care and to assess their long term survival. DESIGN: Prospective. Setting: Tertiary Care Hospital Intensive Care Unit (ICU). SUBJECT AND METHODS: All patients admitted to ICU were enrolled prospectively over a period of 1 year. Children with ICU stay of less than 24 hrs, infants, readmission to ICU were however excluded. Survival was determined at the time of ICU discharge and 1 year later. Health status assessment was done with the help of the multiattribute health status classification (MAHSC), which has 6 domains; sensation, mobility, emotion, cognition, self care and pain. Assessment was done at two points of time - within 48 hours of admission to the ICU and 1 year after discharge. RESULTS: 150 children (mean age 5.68+/- 3.6 years) with a mean duration of ICU stay (5.7 +/- 5.5 days) were included in the study. The cumulative ICU mortality was 12.9%. Fifty-five (36.7% had no overall health impairment (no affected domains) preceding the present illness. There was overall health impairment (?1 affected domain) preceding the present illness in 95 of the 150 patients (63.3%). In the domain specific health status mobility was affected in 74 (49%) followed by pain 61 (41.2%), self care 56 (38.8%), sensation 29 (20%), cognition 21 (14.8%) and emotion 14(9.5%). After 1 year, overall state of health had improved or was equal to the premorbid state in 87 (75%). In domain specific health, the proportion improving or remaining unchanged varied from 75% (emotional) to 80% (cognition), 85.3% (pain) and 88.7% (mobility). The overall state of health had worsened as compared to the premorbid state in 29 (25%) majority with neurological illnesses. CONCLUSION: Quality of life in three-quarters of the patients was preserved and one year survival was favorable. Worsening was noted primarily in-patients with neurological illnesses.