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Assuntos
Humanos , Revestimento de Dentadura , Estética , Seguimentos , Fonética , Taxa de Sobrevida , Dente , TransplantesRESUMO
The aim of this study was to evaluate implant stability placed in the maxillary sinus which was augmented with bovine bone mineral (Bio-Oss.) mixed with autogenous bone from the maxillary tuberosity. Maxillary sinus floor augmentation with the mixture of bovine bone mineral and autogenous maxillary tuberosity bone was performed in 30 maxillary sinuses, and 68 implants were placed at the time of sinus graft. After 6 months of implant placement abutments were connected and implant stability quotient (ISQ) was measured by radio frequency analysis (RFA). In addition, bone level changes was evaluated by taking periapical radiograph. During surgical procedures, no complication was observed, and all patients healed uneventfully. At 6 months the implant showed stable ISQ values. The marginal bone level changes around the fixtures was stably maintained through out the follow up period. This study confirmed that maxillary sinus floor augmentation with mixture of bovine bone mineral and maxillary tuberosity bone could be reliable for bone regeneration in subantral space.
Assuntos
Humanos , Regeneração Óssea , Implantes Dentários , Seguimentos , Seio Maxilar , Levantamento do Assoalho do Seio Maxilar , TransplantesRESUMO
Assuntos
Animais , Humanos , Ratos , Aumento do Rebordo Alveolar , Durapatita , Fator VIII , Adesivo Tecidual de Fibrina , Fibrina , Fibrinogênio , Hemostasia , Polímeros , Pele , Espaço Subdural , Cirurgia Bucal , Suturas , Trombina , Adesivos Teciduais , Extração Dentária , Transplantes , CicatrizaçãoRESUMO
Assuntos
Feminino , Humanos , Masculino , Acidentes de Trânsito , Fraturas Mandibulares , Traumatismos Maxilofaciais , Estudos Retrospectivos , SeulRESUMO
PURPOSE: To determine the role of Insulin-like Growth Factor-I (IGF-I) in the regulation of Vascular Endothelial Growth Factor (VEGF) expression in MG-63 cells and then to find the mechanism b which this regulation occurs. MATERIALS AND METHODS: MG-63 cells were grown to confluence in 60-mm dishes. To determine the effects of IGF-I on expression of VEGF mRNA according to time and concentration, the cells were treated with 10 nM IGF-I, following isolation of total RNA and Northern blot analysis after 1, 2, 4, 8, 12, 24 hours and after 2 hours of treatment with 0.5, 2, 10, 25, 50 nM IGF-I respectively, isolation of total RNA and Northern blot analysis were followed. To determine the mechanism of action of IGF-I, inhibitors such as hydroxyurea (76.1 microgram/ml), actinomycin D (2.5 microgra/ml), cycloheximide (10 microgram/ml) were added 1 hour after treatment of 10 nM IGF-I. RESULTS: 1. the expression of VEGF mRNA was increased with treatment of IGF-I. 2. The expression of VEGF mRNA was increased according to time- and concentration dependent manner of IGF-I. 3. The effect of IGF-I was decreased by hydroxyuera, actinomycin D, but not by cycloheximide. CONCLUSION: IGF-I regulate the expression of VEGF mRNA in the level of DNA synthesis and transcription. These results could suggest that IGF-I plays an important role in angiogenesis in the process of new bone formation and remodeling.
Assuntos
Northern Blotting , Cicloeximida , Dactinomicina , DNA , Hidroxiureia , Fator de Crescimento Insulin-Like I , Osteogênese , RNA , RNA Mensageiro , Fator A de Crescimento do Endotélio VascularRESUMO
Ameloblastoma of the maxilla is an unusual epithelial tumor of odontogenic origin. According to many authors and reports, ameloblastoma account for approximately 1% of all tumors of the jaws, but when pseudo-tumors and cysts are excluded, the ratio rises to 11%. Of these tumors,80% originate in the mandible, while 20% originate in the maxilla. Although it is considered benign histopathologically, it can behave in a slowly growing infiltrative fashion, with multiple recurrences and eventual intracranial, or even distant, spread. We clinically analyzed common site in maxilla, radiographic findings, recurrence rate, duration between treatment and recurrence, the presence and site of distant metastasis in 15 patients who were diagnosed as ameloblastoma of the maxilla and took treatments from 1985 to 1999 in Department of Oral and Maxillofacial Surgery, Dental Hospital, Seoul National University. In this paper, treatment outcomes and our clinical experiences of maxillary ameloblastoma are reported with review of literatures.