Clinical observation on effect of electric acupuncture at Sishencong in treating insomnia / 中国中西医结合杂志

<p><b>OBJECTIVE</b>To evaluate the clinical therapeutic effect of electric acupuncture (EA) at Sishencong (EX-HN 1) on insomnia.</p><p><b>METHODS</b>Two hundred and seventy-six patients were randomly assigned to 2 groups, 138 in each group, the EA group treated with EA at Sishencong, and the control group with oral administration of Tianmeng Capsule. The treatment course for both groups was 3 weeks. The quality and related parameters of sleep before and after treatment were evaluated with a multi-channel sleep detector.</p><p><b>RESULTS</b>After treatment, the quality of sleep was improved in both groups (P < 0.05), as compared with before treatment, the difference in related parameters was significant respectively (P<0.05 or P <0.01), however, the improvement in the EA group was superior to that in the control group (P < 0.01).</p><p><b>CONCLUSION</b>EA at Sishencong has obvious effect on insomnia.</p>

Evaluation of therapeutic effects of synthetic auricular point therapy for treatment of common migraine at the attack stage / 中国针灸

<p><b>OBJECTIVE</b>To observe and evaluate the short-term and long-term curative effects of the synthetic auricular point therapy on the common migraine in attack stage.</p><p><b>METHODS</b>With the study method of randomized controlled trial, 108 cases of common migraine at the attack stage were randomly assigned to a treatment group of 72 cases treated with synthetic auricular point therapy (blood-letting on the ear back, point injection of own blood, pricking ear point), and a control group of 36 cases treated with Western medicine. Their short-term and long-term curative effects were observed and evaluated.</p><p><b>RESULTS</b>The total short-term effective rate and the total long-term effective rate were respectively 98.6% and 79. 6% in the treatment group with less adverse effects, and with a very significant difference as compared with the control group (P < 0.01).</p><p><b>CONCLUSION</b>The synthetic auricular point therapy has obvious short-term and long-term curative effects on common migraine at the attack stage with safety.</p>

Effect of acupuncture at Sishencong (EX-HN 1) on sleeping in the patient of insomnia / 中国针灸

<p><b>OBJECTIVE</b>To assess therapeutic effect of acupuncture at Sishencong (EX-HN 1) on insomnia.</p><p><b>METHODS</b>Sixty-five cases of insomnia were treated with acupuncture at Sishencong (EX-HN 1) and their quality and compositions of sleeping before and after treatment were evaluated with a multichannel sleep detector.</p><p><b>RESULTS</b>After treatment, the quality of sleeping increased significantly (P < 0.05), and the sleeping rate increased from (61.95 +/- 22.90)% before treatment to (79.27 +/- 11.05)% after treatment (P < 0.05).</p><p><b>CONCLUSION</b>Acupuncture at Sishencong (EX-HN 1) has obvious therapeutic effect on insomnia.</p>

Expression of CXCR4 and its effect on the biological behavior of multiple myeloma cells / 中华血液学杂志

<p><b>OBJECTIVE</b>To investigate the effect of stromal cell derived factor-1alpha(SDF-1alpha) expression and its receptor CXCR4 on the biological behavior of multiple myeloma (MM) cells and on the expression of soluble intercellular adhesion molecule 1 (ICAM-1).</p><p><b>METHODS</b>FACS analysis was used to study the expression of ICAM-1 (CD(54)) and CXCR4 on the surface of MM cells. Chemotaxis assay through transwell bore polycaronate and ELISA assay were employed to monitor the soluble ICAM-1 level.</p><p><b>RESULTS</b>(1) Fresh MM cells expressed variable levels of functional CXCR4 [(50.4 +/- 27.3)%], which was correlated with the in vitro ability of transwell migration of MM cells [(23.6 +/- 17.2)%, P < 0.01]. (2) SDF-1alpha could up-regulate the expression of ICAM-1 on MM cells. Furthermore, the serum level of sICAM-1 was correlated with the expression of CXCR4 on MM cells.</p><p><b>CONCLUSION</b>SDF-1alpha/CXCR4 plays an important role on the biological behavior of MM cells via mediating the effect of adhesion molecules.</p>