Dual role of autophagy in hepatitis B virus and related liver diseases / 临床肝胆病杂志

Autophagy is a process of lysosome degradation and has a dual role in the development and progression of diseases, i.e., it can promote cell survival and induce cell death. This article introduces the dual role of autophagy in hepatitis B virus (HBV), chronic hepatitis B, liver fibrosis, and hepatocellular carcinoma and the mechanism of action of autophagy in related liver diseases. It is pointed out that autophagy may be a future research direction for the treatment of HBV-related liver diseases and can provide new ideas for the treatment of liver fibrosis and hepatocellular carcinoma.