RESUMO
Retinal degeneration,associated with loss of photoreceptors,is the primary cause of permanent vision impairment,impacting millions of people worldwide.Age-related macular degeneration and retinitis pigmentosa are two common retinal diseases resulting in photoreceptor loss.Recently,many studies were working on the application of polymer scaffolds in retinal stem cell transplantation.The results showed that polymer scaffolds can delivery transplanted cells to the correct site and promote cell survival,integration,differentiation,thereby providing a good platform for cell transplantation.There are different transplantation cell types.Moreover,different materials have different advantages and disadvantages.The ideal scaffold should have the following characteristics:thin,biocompatible,biodegradable,certain mechanical strength and flexibility,and easy to bind.Surface modification of materials can improve their functioning.In addition to the cells,the scaffold can directional transport substances,such as drugs.Polymer scaffolds have a good prospect in the application of retinal cell transplantation.This paper summarized the findings of different scaffolds for cell delivery to the sub-retinal space-based transplant technology.
RESUMO
Learning modes based on the initiatives of students has become a new way in the development of medical students' quality.The second clinical medical college of Southern Medical University performed an improved teaching method:meliorated PBL based on TBL and taking clinical and scientific research ability as the core,which combined the advantages of PBL and TBL in view of the importance of clinical and scientific research ability for medical students.Practice proved that this teaching method was effective in improving comprehensive quality of medical students and cultivating more comprehensive talents for the society.