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Objective:To investigate the present situation of unintended pregnancy within two years postpartum and its influencing factors in China.Methods:Participants who delivered a live birth at 60 hospitals in 15 provinces in the eastern, central and western regions of China during July 2015 to June 2016 were interviewed by using structured questionnaire. Information on occurrence of unintended pregnancy within 2 years after delivery, postpartum contraceptive use, sexual resumption, breastfeeding, and women′s socio-demographic characteristics, and so on, were collected. Life-table analysis, cluster log-rank tests and a 2-level Cox regression model were used for data analysis.Results:A total of 18 045 postpartum women were investigated. The cumulative 1- and 2-year unintended pregnancy rates after delivery were 5.3% (95% CI: 4.5%－6.1%) and 13.1% (95% CI: 11.3%－14.8%), respectively. Cox regression model analysis showed that the risk of unintended pregnancy within 2 years postpartum were increased in younger women, ethnic minorities, women with abortion history, and those who had a vaginal delivery with short lactation time and late postpartum contraceptive initiation (all P<0.01). The risk of postpartum unintended pregnancy was not associated with geographic regions and hospitals where women gave a birth (all P>0.05). Conclusions:In China, the risk of unintended pregnancy within 2 years after delivery is relatively high. Service institutions and service providers should improve the quality of postpartum family planning services, promote the use of high effect contraceptive methods, and educate women to use a method at the time of their sexual resumption or even before.
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Objective To investigate the effect of Astragalus membranaceus on the antioxidant capacity and liver and kidney function in patients with chronic schizophrenia and metabolic syndrome.Methods 110 cases of patients with chronic schizophrenia and metabolic syndrome were selected as subjects.They were randomly divided into the control group and the observation group by random number table method.Both groups were treated with routine antipsychotic drugs, and the observation group were additionally treated with Astragalus injection, once per day.10~14 d as a course of treatment, they were treated for a total of 6 courses.The antioxidant capacity and the liver and kidney function were compared between the two groups.The mental symptoms was evaluated with the positive and negative symptoms scale(PANSS).Results After treatment, the antioxidant capacity of the two groups was significantly increased while MDA was significantly decreased, and the changes were more obvious in observation group than the control group.After treatment, indexes of liver and kidney function were significantly increased.Except BUN and SUA, the other indicators were better in the observation group than the control group(P<0.05).After treatment, PANSS score (61.4±7.8)in the control group was significantly higher than that of the observation group(54.5±8.2)(P<0.05).Conclusion Astragalus membranaceus can be used as an assisted drug for treating chronic schizophrenia and metabolic syndrome.It can effectively improve the antioxidant capacity, reduce the damage to liver and kidney function and improve symptoms of mental illness, so as to improve the quality of life.
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Objective To investigate the surgical strategy for degenerative lumbar scoliosis (DIS)and evaluate the clinical results of the posterior correction and fusion technique. Methods From May 2003 to May 2009,27 patients with DIS were treated posterior operation. All the patients were performed posterior laminectomy,spinal fusion and correction with pedicle screws system. Among the patients, 18 cases with posterolateral bone grafting,9 cases complicated spondylolishesis with PLIF intervertebral combined with posterolateral fusion. Results All the cases were followed up for a minimum of 12 months and 88.9% (24/27) of them had excellent or good outcome, Oswestry score was(21.54 ± 1.95 )%;22 cases were followed up for 24 months and showed a rate for excellent or good results of 86.4%( 19/22),and Oswestry score was (24.26 ± 2.32)%. Oswestry scores of the postoperative 12,24 months were lower than that before operation (57.83 ± 2.71 )%. There was statistical difference in the cases preoperation and postoperation. Correction of scoliosis of the coronal plane was 47.2%. Preoperative lumbar lordosis was augmented from 23.6°± 8.3° to 43.8°± 9.1°. One case complicated with wound infection during perioperation period, and 2 eases with heart diseases. The screw of 1 case was loosening at 3 months postoperation. Conclusion Decompressing thoroughly and improving lumbar lordosis, the operation of posterior correction and bone graft fusion shows good results for degenerative lumbar scoliosis.