Risk factors for mortality in patients with severe fever with thrombocytopenia syndrome / 中华传染病杂志

Objective To analyze the clinical features and risk factors for mortality of patients with severe fever with thrombocytopenia syndrome (SFTS) in Zhoushan, the eastern coastal of China with high incidence of severe fever with thrambocytopenia syndrome bunyavirus infection, to provide reference for reducing the mortality rate of SFTS.Methods Clinical data of 107 cases of SFTS from Zhoushan Hospital during June 2011 to June 2016 were retrospectively analyzed.According to the prognosis, patients were divided into survival group and death group.The clinical features and the laboratory results were analyzed with a case-control method to analyze the prognostic factors.Normal distribution data were compared with the independent t test.Kolmogorov-Smirnov Z test were used in data with skewness distribution.Categorical data were analyze by chi-square test.The related risk factors were analyzed with the receiver-operating characteristic (ROC) curve and multivariate unconditioned logistics regression analysis.Results Seventeen cases among 107 STFs patients died, yielding the mortality rate of 15.9%.The proportion of patients suffering from two or more underlying diseases, with disorders of consciousness, activated partial thromboplastin time (APTT), the level of creatine kinase (CK), lactate dehydrogenase (LDH) as well as sepsis-related or sequential organ failure assessment (SOFA) score in death group were all significantly higher than those in the survival group (all P73.45 s, SOFA scores >9 were the independent risk factors for mortality of SFTS (OR=6.947, 8.459 and 11.770, respectively, all P<0.05).Conclusion Ca2+, APTT and SOFA score are the independent risk factors for prognosis of SFTS, which provide reference for prognostic evaluation of SFTS.

Status quo research on the information literacy of the young faculties in medical Universities and corresponding promotion strategies——Based on a survey in Peking University Health Science Center / 中华医学科研管理杂志

As the new force among university faculties,the young faculties are the backbone of teaching and research activities in universities and the main information users concerned for information access.To understand the actual condition of information literacy of young faculties in Peking University Health Science Center and grasp their difficulties in getting access to information,this study analyses the information literacy of young faculties through investigating the status quo of their information capabilities,gathering their suggestions and opinions to enhance information capabilities and retrieval tests conducted among small-scale young faculties.The survey results show that 72％ of young faculties don't know or know little about the four biomedical literature retrieval databases and 47％ of them knowing nothing about CALIS.This suggests we should take measures to promote the information literacy of young faculties.