Structure determination of five trace chemical constituents from roots of Linum usitatissimum / 中国中药杂志

<p><b>OBJECTIVE</b>To investigate the trace chemical constituents from the roots of Linum usitatissimum.</p><p><b>METHOD</b>Isolation and purification of the trace constituents were carried out mainly by solvents extraction and macroporous adsorbing resin and silica gel column chromatography. The structures of the isolates were elucidated by extensive spectroscopic analysis,including 1D and 2D NMR, MS, and HRMS.</p><p><b>RESULT</b>Five trace compounds were isolated and identified as 3-methyl-2, 5-pyrrolidinedione-5-oxime (1), hypoxanthine (2), nonanedioic acid-1,9 (3), and the mixture of isoleucine and leucine(4 and 5).</p><p><b>CONCLUSION</b>Compound 1 is a new compound, and compounds 2-5 are isolated from L. usitatissimum for the first time.</p>

Clinical Study of Interventions of Nosocomial Infection in Comprehensive Intensive Care Unit / 中华医院感染学杂志

OBJECTIVE To strengthen management of nosocomial infections in comprehensive intensive care unit so as to enhance medical treatment quality.METHODS Nosocomial infection administration department constituted the management institutions and standards of nosocomial infections with supervising,implementing targets monitoring.Comprehensive intensive care unit instituted several groups of nosocomial infection management and fulfiled the precautions and control measures.RESULTS By means of interventions and prophylaxes,the occurrence of nosocomial infection in comprehensive intensive care unit decreased.CONCLUSIONS It ensures for medical treatment quality and safe by strengthening the management of nosocomial infections.

Studies on chemical constituents of roots of Linum usitatissimum / 中国中药杂志

<p><b>OBJECTIVE</b>To study the chemical constituents from the roots of Linum usitatissimum.</p><p><b>METHOD</b>The compounds were isolated and purified by silica gel column chromatography, their structures were elucidated by physico-chemical properties and spectroscopic data.</p><p><b>RESULT</b>Ten compounds were isolated and identified as vanillic acid (1), syringic acid (2), xanthine (3), vitexin (4), isovanillin (5), (E)-3,3'-dimethoxy-4,4'-dihydroxystilbene (6), tachioside (7), beta-sitosterol and stigmasterol (8 and 9) mixture, berberine (10).</p><p><b>CONCLUSION</b>Compounds 1-3, 5-7, 10 were isolated from L. usitatissimum for the first time.</p>