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Objective The standardization of traditional Chinese medicine(TCM)term in English is a precondition for the internationalization of TCM.Therefore,in the current study similarities and differences on visceral terms between 2022 World Health Organization International Standard Terminologies of Traditional Chinese Medicine(abbreviated as WHO22)and the existing International Standard Chinese-English Basic Nomenclature of Chinese Medicine compiled by the World Federation of Chinese Medicine Societies(abbreviated as ISNTCM)and the WHO International Standard Terminologies on Traditional Medicine in the Western Pacific Region(abbreviated as ISTTM)were discussed.Methods The electronic versions of the existing terminology standard were collected,and terms on viscera section were extracted and converted into Excel files.Terms on visceral section in the WHO22 were also processed with the same method.The similarities and differences between WHO22 and ISNTCM as well as those between WHO22 and ISTTM were compared.Results In the WHO22,there are 170 terms on viscera section,in ISTTM,there are 83 terms,and in ISNTCM 215 terms.Generally,ISTTM and WHO22 are consistent in visceral terms,but in WHO22 the names of the five zang-organs,six fu-organs,and extraordinary fu-organs as single terms are not listed.ISNTCM and WHO22 share the same visceral terms with slight difference.Conclusion WHO22 reflects the latest achievements of the English translation standard of TCM,and is the result of study and cooperation between Chinese and foreign scholars.However,there are inconsistencies in translations of certain terms,which might be caused by no clarification on translation principles or term selection principles.Besides,new research method such as corpus linguistics are not applied in the context of the rapid development of information technology in WHO22.
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Objective To explore the effects of movement on hippocampal β-amyloid protein ( Aβ ) and amyloid precursor protein (APP) in senescence-accelerated and senescence-prone (SAMP8) mice, and the mechanism by which movement improves learning and memory in mice with a model of Alzheimer's disease. Methods Forty 3-month-old SAMP8 mice were divided randomly into a movement group and a control group. The movement group was trained with a running wheel 10 min daily, 5 days a week in the first month, and 20 min daily in the second month. Morphological changes in the hippocampus were observed under the microscope after HE staining. The expression of Aβ in the hippocampus was detected by immumohistochemical methods and APP mRNA expression was detected by RT-PCR two months later. Results HE staining showed neuron degeneration and death, chromatin condensation and vacuolar degeneration in the hippocampus of the 5-mouth-old SAMP8 mice of the control group. The movement group showed less neuron degeneration and death, and the morphology of most cells was normal The expression of Aβ in the hippocampus of the 5-month-old SAMP8 mice in the movement group was significantly lower than that in the control group. APP mRNA expression levels in the movement group were also significantly lower.Conclusions Movement can delay neuron degeneration and down-regulate Aβ and APP mRNA expression levels in the hippocampus of SAMP8 mice. It may be an important mechanism by which movement improves learning and memory in mice with a model of Alzheimer's disease.
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Objective To investigate the roles of cytokines and non-bioartificial liver in mechanism and clinical treatment of severe hepatitis.Methods Serum IL-2,IL-6,TGF?_1,TNF-?,sFas,IFN-?levels of severe hepatitis patients before and after treatment with non-bioartificial liver were detected and compared.Results Serum IL-2 and IFN-?levels in severe hepatitis group before treatment were obviously lower than those of normal control group(P