Preparation and Characteristic of Monoclonal Antibodies against Tetrodotoxin / 第二军医大学学报

0.05). (4) The result of detoxincation in- vivo was not as good as that of antiserum.

EFFECTS OF SYSTEMIC POISONING BY SULPHUR MUSTARD ON CELL DNA BIOSYNTHESIS OF INTERNAL ORGANS AND PROTECTIVE ACTION OF ANTIDOTES IN MICE / 第二军医大学学报

In this study, we observed the efTects of systemic poisoning by sulphur mustard (SM) on DNA biosynthesis of internal organs and protective action of antidotes in mice.The results showed that the systemic poisoning by SM produced a strong depression of [3H]-TdR incorporation into DNA biosynthesis, which was characterized by rapidity, severity and rapid recovery.It is suggested that mammal an organism has a marked physiological compensation, regeneration and repair activity for DNA damage.Antidote sodium thiosufate alone or in combination with unithiol (DMPS) has satisfactory protective effects on depression of DNA biosynthesis in mice poisoned by SM.