Status quo of global bioindustry and its policy implications / 生物工程学报

The advent of the bioeconomy era is triggers a new wave of technology and industrial revolution. Bioeconomy has become the commanding heights that major developed countries and emerging economies try to seize. This paper analyzes the spatiotemporal characteristics of global bioindustry development from four perspectives: biomedical industry, genetically modified crop planting industry, bioenergy industry, and bio-based chemical industry. Then it summarizes the main characteristics of the development of the global bioindustry, and further put forward policy recommendations for the bottleneck problems in the development of China's bioindustry, which can guide the future development of China's bioeconomy.

Assessment and empirical analysis of the competitiveness of bioindustry in various regions of China / 生物工程学报

The era of bioeconomy has ushered in a new wave of technological and industrial revolution for mankind. The strategic deployment for the bioindustry in China has achieved remarkable results. However, there are still problems such as unbalanced regional development in the process of bioindustry development. In order to comprehensively assess the current situation of the competitiveness of the bioindustry in various regions of China, the assessment indicator system of the overall competitiveness of the bioindustry is constructed from the perspective of the four sub-industries of biomedicine, bioenergy, bioagriculture and bio-based industry. The weight of each assessment indicator is determined by the analytic hierarchy process. According to geographical administrative division and regional economic relations, an empirical analysis of the comprehensive competitiveness score of the bioindustry in seven regions of China is carried out. The assessment results show that the competition of bioindustry in various regions of China presents a gradient distribution in space. In view of this, relevant policy recommendations are put forward from four aspects: (1) implementing the strategy of rural revitalization, (2) implementing the strategy of regional coordinated development, (3) deepening the supply-side structural reform for the bioindustry, and (4) establishing regional unified information collaboration network system.

Pathogenesis of viral myocarditis / 心血管康复医学杂志

Viral myocarditis (VMC) is a clinical frequent cardiovascular disease with extremely high mortality and disability rate ,which seriously impairs the health of children and young adults ,and its pathogenesis has not been fully elucidated .It is generally believed that VMC pathogenesis is mainly related to direct damage on myocardial cells ,immune damage ,cell apoptosis and cytokines .The present article made a summary about the research progress of its pathogenesis .

Effect of integrin-linked kinase in heart disease / 心血管康复医学杂志

Interin-linked kinase (ILK)is a kind of effector of intra-and extracellular biological signal transduction,partici-pating in the formation of multiple signal pathways,it plays an important role for occurrence and development of heart dis-eases such as cardiac hypertrophy,coronary heart disease,viral myocarditis,dilated cardiomyopathy etc..

Mutatitions of X region nucleotide sequence of hepatitis B virus DNA in the patients with chronic hepatitis B / 中华传染病杂志

Objective To investigate the mutations of HBV X region nucleotide sequence in the patients with chronic hepatitis B. Methods X region fragments of HBV DNA from 24 patients were amplified by polymerase chain reaction and sequenced. Results There were 2 15 point mutations in X region from the 24 hepatitis patients studied. The A to T mutation at nt1762 and G to A mutation at nt 1764 were found in 11 cases. The combined mutation at nt1636-1741 were found in 8 cases.Conclusions The results indicated the combined mutations of nucleotide(nt) 1762 and 1764 was associated with HBeAg(-) in the patients with chronic hepatitis.