Observation on the therapeutic efficacy of Tuina plus "three-bridge" exercise for non-specific low back pain / 针灸推拿医学（英文版）

Objective: To investigate the efficacy of Tuina (Chinese therapeutic massage) plus "three-bridge" exercise for non-specific low back pain (NSLBP). Methods: A total of 80 patients with NSLBP were randomly divided into a control group and an observation group according to the random number table method, with 40 cases in each group. The two groups received Tuina treatment, and the observation group received an additional "three-bridge" exercise. The treatment lasted 4 weeks, and a follow-up evaluation was carried out 6 months after treatment. The visual analog scale (VAS), Oswestry disability index (ODI), and the Japanese Orthopaedic Association (JOA) scores for low back pain were used to evaluate patients' conditions before treatment, after 4-week treatment, and at the 6-month follow-up. Results: The total effective rate was 92.5％ and 85.0％ in the observation group, respectively, after 4-week treatment and at the 6-month follow-up, significantly different from the control group (P<0.05). After 4-week treatment and at the 6-month follow-up, the VAS, ODI, and JOA scores of the two groups were improved compared with those before treatment (P<0.05), and all the indicators in the observation group were significantly better than those in the control group (P<0.05). At the 6-month follow-up, the VAS, ODI, and JOA scores in the two groups were improved compared with those before treatment (P<0.05). Conclusion: Tuina plus "three-bridge" exercise can effectively alleviate pain, improve function, and have relatively sound long-term effects in treating patients with NSLBP.

Research Progress of Radiotherapy Combined with Immune Checkpoint Inhibitors in Treatment of Glioblastoma / 肿瘤防治研究

Glioma is the most common primary intracranial tumor, and most patients present as glioblastoma, with high morbidity and mortality. The prognosis of patients with glioblastoma remains poor after surgical resection combined with standardized treatment of radiotherapy and chemotherapy. In recent years, although the breakthrough of immunotherapy have been achieved in the treatment of a variety of solid tumors, the existing data show that immunotherapy is not effective in improving the survival of patients with glioblastoma. However, studies have shown that immunotherapy can have a synergistic effect with radiotherapy which can increase antigen presentation and promote the formation of pro-inflammatory tumor microenvironment, providing more relevant targets for immunotherapy. The purpose of this paper is to discuss the effect of radiotherapy on tumor immune microenvironment and the role of radiotherapy combined with immune checkpoint inhibitors in the treatment of glioblastoma.

Application of damage control surgery in treatment of severe electric burn / 实用医学杂志

Objective To explore the effect of damage control surgery (DCS) in the treatment of severe electric burn. Methods Retrospective analysis on clinical data of 45 patients with severe electric burn was con-ducted. According to implementing DCS or not , patients were separated into DCS group and control group. In DCS group, tangential excision and transplanted xenogenic acellular dermal matrix was conducted for severe electric burn cases with deep Ⅱ degree wound, and escharectomy and VSD dressing for Ⅲ~Ⅳ degree electric contact burn wound at the first stage then skin-grafting or skin flap-grafting on the secong stage was applied. For control group , debridement, tangential excision or escharectomy and skin-grafting or skin flap-grafting to close the wound were conducted. We compared the difference in terms of operation time, length of stay, disability rate, mortality and complications between 2 groups. Results The operation time, incidince of disability and complications in DCS Group obviously decreased but there was no difference in length of stay and mortality in both groups. Conclusion DCS is effective for reducing complications and optimizing therapeutic effect for severe electric burn patients.

Detection and analysis of lead concentrations in the blood of children in Xiamen / 国际检验医学杂志

Objective To provide the scientific guidance for the prevention of lead poisoning in the children ,the lead concentra‐tions in the blood of children in Xiamen are investigated .Methods 11 271 cases of outpatients with the age of 0 -10 years old in maternity and child care hospital were surveyed randomly .The lead concentrations in the blood of these children were determined by graphite furnace atomic absorption spectrometer .Results From 2010 to 2013 ,the whole blood lead levels of 11 271 children was detected .The mean blood lead levels was 51 .0 μg/L .The boy lead poisoning rate was higher than girls in different age groups ,the difference was statistically significant (P<0 .05) .Both the above indices increased gradually with the increase of age in the range of 1-6 years old ,and the mean blood lead levels reached its peak in preschool age ,the mean blood lead did not increased in school‐age children ,and the lead poisoning rate showed the downward trend .Conclusion The lead poisoning rate of children in Xiamen is close to the average level of other cities ,however ,the blood lead level tends to increase with the increase of age .The effect of lead pollu‐tion on physical health of children shall be paid more attention to nowadays .

Clinical observation on transurethral electrocision for the treatment of prostatic cyst / 中国医师进修杂志

Objective To evaluate the efficacy in treatment with transurethral electrocision for prostatic cyst.Methods A total clinical documents of 15 cases prostatic cyst treated with transurethral electrocision were analyzed retrospectively.All the cases were diagnosed confirmly by ultrasonography and CT,all the cysts closed to the prostatic urethra or intrude urinary bladder and all the patients underwent transurethral electrocision.Results All operations were performed successfully with operative time of 18-60 (36 ± 13) min.No blood transfusion during and after the operation and postoperative hospital stay was (5.2 ± 2.6) d.All the patients had been followed up for 6-24 months,the clinic symptom disappeared and no complications happened.Three months after the operation,IPSS decreased from (27.2 ±5.6) scores to (7.5 ± 1.6) scores and QOL decreased from (4.5 ± 1.1 ) scores to ( 1.6 ± 0.6) scores (P＜ 0.01 ),respectively.Qmax increased from (6.8 ±2.3) ml/s to (22.4 ±4.8) ml/s (P ＜0.01).Conclusion Transurethral electrocision is an effective therapeutic measure of prostatic cyst close to the prostatic urethra or intrude urinary bladder without so many complications.