Preoperative MRI staging in diagnosis of tongue squamous cell carcinomas / 中国医学影像技术

Objective To observe the value of MRI in preoperative staging of tongue squamous cell carcinomas (TSCC).Methods Totally 154 patients with TSCC underwent MR scanning.MR manifestations of TSCC were analyzed,and the preoperative staging of Tumor (T),Node (N) and American Joint Committee on Cancer (AJCC) were performed.Then the consistency between preoperative MRI staging and postoperative pathology staging was evaluated.Results Preoperative MRI T staging were T1 in 37 patients,T2 in 54,T3 in 7 and T4 in 56 patients,respectively,while N staging were N0 in 104 patients,N1 in 31 and N2 in 19 patients,respectively.For AJCC staging,there were 34 patients in Ⅰ stage,37 in Ⅱ stage,21 in Ⅲ stage and 62 in Ⅳ stage,respectively.Between preoperative MRI and postoperative pathology staging,the Kappa of T,N and AJCC staging was 0.814,0.786 and 0.790,respectively (all P＜0.01).The accuracy rate of preoperative MRI T,N and AJCC staging of TSCC was 87.01％ (134/154),88.96％ (137/154) and 85.06％ (131/154),respectively.Conclusion The consistency was good between preoperative MRI T,N and AJCC staging and postoperative pathology staging of TSCC.

CT and CTA Diagnosis Of Intracranial Hemangiopericytoma / 中国医学影像学杂志

Purpose To investigate the CT and CTA findings of intracranial hemanigoperiocytoma. Materials and Methods The CT and CTA data of 7 cases of pathologically confirmed intracranial hemanigoperiocytoma were retrospectively reviewed. Results All the 7 cases were extra-axial and supratentorial location. Six were lobulated and 1 were oval in shape. Three were iso-density to the parenchyma and 4 were inhomogeneous with clear margins. Five had perifocal edema. On contrast scan, all showed homogeneous or inhomogeneous enhancement. Five had dilated tortuous vessels and 4 were identified as feeding artery inside or around the tumors. Conclusion The CT findings of intracranial hemanigoperiocytoma are similar to meningioma but CTA is helpful for the differential diagnosis.

Effects of TIMP-3 gene transient expression on proliferation,migration and apoptosis of rabbit vascular smooth muscle cells / 基础医学与临床

Objective Observe effects of TIMP-3 gene transient expression on proliferation,migration and apoptosis of VSMCs.Methods Transfect VSMCs separately in three groups as control,empty plasmid and recombinant group mediated by cationic liposome.First,calculate cells,quantify MMP-2 and analyse TIMP-3 mRNA at 24,48 and 72 h;Second,measure cell apoptosis rate and calculate migrated cells as well after 48 h.Results There were no difference between control group and empty plasmid group in cell growth,MMP-2's content,TIMP-3 mRNA expression and apoptosis rate,cells migration rate;but those of recombinant group were greatly different in other two(P