Effect of early and late endarteritis upon clinical prognosis after renal transplantation / 中华器官移植杂志

Objective:To explore the clinical prognosis of early endarteritis (within 2 weeks) and late endarteritis (after 2 weeks) after renal transplantation.Methods:A total of 81 cases with higher creatinineand receiving renal biopsy after renal transplantation were recruited from September 2001 to December 2014. They were divided into early endarteritis group (n=43) and late endarteritis group (n=38). Baseline profiles, serum creatine, glomerular filtration rate (GFR) before and after treatment, steroid resistance, reversal rate, graft loss and survival rate were analyzed for two groups.Results:Early endarteritis group showed worse serum creatine and GFR than late endarteritis group before rejection. Early endarteritis group had a higher rate of treatment with steroid plus antibody (86 %) than that of late endarteritis group (86 %vs.18.6 %, P<0.05). No significant inter-group difference existed in graft loss (23.3 % vs.10.5 %, P=0.131). The survival curve of transplanted kidney showed no significant inter-group difference insurvival time. Conclusions:The status of patients with early simple endothelitis is significantly worse than that of those with late simple endothelitis. However, after active treatments, the prognosis of patients with early simple endothelitis is not inferior to that of those with late simple endothelitis.

Analysis of Antibiotics Used by Medical Insured Inpatients with Lung Infection / 中国药房

OBJECTIVE: To investigate the use of antibiotics in medical insured inpatients with lung infection for reference of management of expenditure of antibiotics in the inpatients.METHODS: The data base documents of a total of 685 insured inpatients with lung infection(Jan.2004～Jun.2006) were collected for a statistical analysis in respect of the utilization and expenditure of antibitoics using defined daily dose and the ratio of order of consumption sum to that of DDDs as indexes.RESULTS: Cephalosporins and quinolones took the lead in expenditure and DDDs,accounting for 70.70% of total antibiotics in terms of consumption sum.CONCLUSION: The main factors affecting hospitalization expense were the application of cephalosporins and quinolones,thus emphasis should be paid to the supervising of these factors.