Correlation between physical activity and depressive symptoms in adolescents / 中国学校卫生

Objective@#To analyze the correlation between physical activity and depressive symptoms in adolescents, so as to provide a reference for the early prevention of depression among adolescents.@*Methods@#Using a random cluster sampling method, 8 102 adolescents from Shanghai, Urumqi, Changsha and Kunming were investigated via the Physical Activity Assessment Questionnaire of Chinese Children and Adolescents aged 7 to 18 and the Center for Epidemiologic Studies Depression Scale (CES-D) for physical activity and depressive symptoms. Multivariate Logistic regression analysis was used to analyze the correlation between physical activity and depressive symptoms in adolescents.@*Results@#The proportion of adolescents who met moderate to vigorous physical activity (MVPA) standard was 37.0%, and the detection rate of depressive symptoms was 25.6%. The detection rate of depressive symptomsin compliant with MVPA standard group was significantly lower than that in non compliant group among different age and gender( χ 2=7.62-34.54, P <0.05). Adolescents with severe depressive symptoms had high light intensity physical activity(LPA) duration and low vigorous intensity physical activity(VPA) duration, while adolescents with mild depressive symptoms or asymptomatic adolescents had higher MVPA duration. There were differences in LPA and VPA among adolescents with different levels of depressive symptoms in the overall sample, and the differences were still significant among girls, middle school and statistically significant differences in LPA, moderate intensity physical activity(MPA), MVPA were also found among the high school subgroup. However, differences only in LPA were observed among boys with different levels of depression( H=46.48, 10.31, 25.02, 29.54, 30.25, 19.80, 22.20, 9.54, 8.62, 18.06, P <0.05). Multivariate Logistic regression model showed that gender and duration of MVPA were significantly related to risk of depressive symptoms( OR=1.56, 1.42, P <0.05).@*Conclusion@#Physical activity among adolescents is significantly related to depressive symptoms. MVPA may be an effective measure to reduce the degree of depressive symptoms.To improve the physical health and prevent depression among adolescents, it is important to choose appropriate physical activity types and effectively increase the duration of MVPA.

Clinical characteristics analysis of 2 368 patients with traumatic brain injury / 中华创伤杂志

Objective To understand the clinical characteristics of traumatic brain injury (TBI) patients and provide fundamental data for reducing the incidence of TBI and improving its treatment efficacy.Methods Medical histories of TBI inpatients from January 2011 to December 2016 were collected from the TBI database of Neurosurgical Department at Tianjin Medical University General Hospital.Information including gender,age,causes of TBI,injury severity,sources of the inpatients,interval from injury to treatment,diagnosis,and treatment were analyzed retrospectively.Results A total of 2 368 TBI patients were enrolled,aged mainly 30-60 years.There were more male patients (n =1 741) than female patients (n =627) (2.78 ∶ 1),while the gender ratio was reversed among patients above 60 years old (2.09 ∶ 1) (P ＜ 0.05).Traffic accident (60.14％) remained the major cause of TBI,while the proportion of electric motorcycle accident was 17.35％,followed by fall from height (13.64％).The proportion of mild TBI patients from suburb counties was lower than that of patients from the six urban areas (P ＜ 0.05),while the proportion of heavy TBI patients from other provinces was higher than those of both urban and suburb counties (P ＜ 0.05).The average interval from injury to specialist treatment was 7.53 hours.Patients who received treatment within 3 hours had better improvement than those who were treated 3 hours after TBI (P ＜ 0.05).The main injuries were skull fracture (33.07％) and brain contusion (30.32％).A total of 783 patients (33.07％) underwent surgery,among which 693 patients received the most common procedure of craniotomy hematoma evacuation (including decompressive craniectomy).The improvement rate of patients with intracranial pressure monitoring was higher than those without intracranial pressure monitoring (P ＜ 0.05).The improvement rate of the surgery group was significantly higher than that of the non surgery group (P ＜0.05).Conclusions The ratio of elderly female TBI patients is on the rise;TBI presents an increase in traffic accidents;mild TBI patients choose to receive treatment in close hospitals while those with severe TBI choose comprehensive hospitals;and the interval from injury to treatment is long.The following strategies including improving the traffic facilities,strengthening the education of traffic safety on elderly females and pedestrians,and optimizing the TBI medical treatment process would reduce the incidence of TBI and improve the efficiency of treatment.

Study on correlation between postoperative coagulation function and fibrinolytic activity indexes with deep vein thrombosis in patients with traumatic fracture / 国际检验医学杂志

Objective To investigate the correlation between the coagulation function and fibrinolytic activity with deep venous thrombosis (DVT) after traumatic fracture operation.Methods One hundred and thirty-four cases of traumatic fracture from April 2010 to May 2014 were divided into the DVT group(24 cases) and non-DVT group,and at the same time 110 healthy people were selected as the control group.The venous blood at different time points was collected for observing the levels change of prothrombin time (PT),activated partial thromboplastin time (APTT),fibrinogen (FIB),platelet aggregation rate (PAgT),dipolymer (D-D),thrombin antithrombin complex (TAT),plasminogen activity (PIg) by using appropriate methods.Results There was no difference in APTT and PT groups among the groups(P>0.05).Preoperative FIB,PAgT,D-D and TAT levels was the DVT group >non-DVT group > control group,while the level of PIg was the DVT group0.05).Conclusion The increase of D-D and TAT is closely related with DVT in traumatic fracture and,which is an independent risk factor.

Study on the connection between adiponectin and chronic hepatitis B associated with liver fibrosis / 中国医师进修杂志

Objective To explore the adiponectin expression in the chronic hepatitis B (CHB) patients and compare the level of edipanectin before and after antiviral therapy, and investigate the relationship between ediponectin and CHB. Methods Serum adiponectin was detected by enzyme linked immunosorbent assay (ELISA), and the expression of adipanectin in liver tissue was detected by palymerase chain reaction (PCR) and immunohistochemistry. The liver functions and HBV DNA were also tested. Liver biopsy tissue was assessed by fibrosis stage. Results Serum adipanectin in CHB liver cirrhosis [(20.65 ± 1.29) mg/L]was higher than that in other stage fibrosis, the values were (8.57 ± 0.28 ), (12.22 ± 0.64), (15.22 ± 0.77 ) mg/L (P< 0.01 ). Serum adiponectin was positively associated with fibrosis stage(r = 0.976,P< 0.01 ). There was no significant difference between HBV DNA and ALT (P> 0.05 ). Serum adipanectiu was independently associated with liver cirrhosis (r = 1.07, P = 0.02, 95% CI = 1.00-l.14).At the end of antiviral therapy,the expressions of adiponectin declined in patients with improved fibrosis and sustained viral response. Conclusion Serum adiponectin may play a role in CHB fibrosis, and reduced adipanectin level is associated with improved fibrosis after antivital therapy.

Follow up Screening of Extraction Process of Volatile Oil in Supplemented Xanthium Powder by GC MS / 中成药

Objective: To screen the extraction process of volatile oil in Supplemented Xanthium Powder.Methods: The main compositions of volatile oil contained by every herb in prescription were followed up by GC MS. Results: The extraction process of volatile oil in Supplemented Xanthium Powder was established, that is, Flos Magnoliae and Cortex Moutan Radicis were powdered, their volatile oils were extracted with Herba Menthae together by the steam distillation; then 13 fold first fraction of distillata and 3 fold redistillation liquid were collected respectively; the volatile oil of Rhizoma Liqustici Chuanxiong was extracted with alcohol. Inasmuch as Fructus Xanthii and Radix Angelicae Dahuricae contained less volatile oil, at the same time, to avoide that Fructus Xanthii produced toxicity by water extraction and coumarinic lactones of Radix Angelicae Dahuricae was destroyed their oils were considered unfit for extraction. Conclusion: GC MS is a useful way for follow up optimization of the extraction process of volatile oil in compound prescription of Chinese medicinal and worthy of popularization.