Pemphigus Vulgaris in Pregnancy Associated with Herpes Virus Type 1 Infection

No abstract available.

Giant Cell Tumor of Tendon Sheath Occurring on the Inguinal Area in a Child / 대한피부과학회지

No abstract available.

Correction of Temporal Triangular Alopecia with Follicular Unit Hair Transplantation / 이화의대지

Temporal triangular alopecia is a triangular or oval shaped non-scarring alopecia, occurring on the temporal side of a scalp. Although surgical excision or hair transplantation has been known to be an effective therapy for this condition, so far only a few case reports have proved their usefulness. A 27-year-old male patient presented with a history of congenital hair loss affecting left frontotemporal area which persisted after simple excision done 10 years ago. We transplanted 270 follicular units into the alopecic patch using follicular unit hair transplantation method. About 75% of alopecic patch was covered with newly grown hairs 15 months after hair transplantation and the patient was satisfied with the result. Herein, we report a case of temporal triangular alopecia which underwent both simple excision and hair transplantation, which provides information about the benefit and loss for each procedure.

The Significance of Home Care Wound Management after Dermatologic Surgery / 대한피부과학회지

BACKGROUND: As the number of dermatologic surgical procedures increases, home care wound management is growing in frequency. OBJECTIVE: The aim of this study was to evaluate the efficacy and surgical site infection rate of home care wound management according to the use of oral antibiotics and the characteristics of the wound and of the patient. METHODS: Our study included 207 patients that had undergone a dermatologic surgical procedure and the subsequent management of their wounds in the home. We checked overall infection rate of home care wound management and compared the result according to the use of oral antibiotics. We evaluated surgical site infection rate after we classified each surgical wound based on age, sex, surgical method, site, size, and depth. In addition, we surveyed efficacy of home care wound management. RESULTS: Overall surgical site infection rate was 1.86%, and the infection rate was not significantly different between the group that utilized home care wound management without oral antibiotics and the group with oral antibiotics (p>0.05). There was no statistically significant difference of surgical site infection rate according to sex, age, wound's size and depth (p>0.05). However, patients with younger age, male sex, greater size, and depth of wounds showed a numerical increase in surgical site infection rate. Staged partial excision for nevus sebaceous in scalp showed significantly higher rate of surgical site infection (p<0.05). In our survey, most patients preferred home care wound management after dermatologic surgical procedures and patients were able to perform the wound care well. CONCLUSION: We expect to utilize home care wound management after dermatologic surgical procedures, provided that physicians appropriately educate patients and their caretakers on proper dressings.

Extramammary Paget's Disease of External Genitalia with Bowenoid Features

Extramammary Paget's disease (EMPD) is an uncommon intraepithelial adenocarcinoma, primarily affecting the apocrine-bearing skin. Bowen disease is an intraepithelial squamous cell carcinoma having the potential to become invasive carcinoma. The histopathological concomitant features between EMPD and Bowen disease have been described. One theory is that primary EMPD arises multicentrically, within the epidermis from the pluripotent stem cells. Herein, we describe a case of EMPD that had bowenoid features, and review the previous cases associated with the origin of EMPD.

Extramammary Paget's Disease of External Genitalia with Bowenoid Features

Extramammary Paget's disease (EMPD) is an uncommon intraepithelial adenocarcinoma, primarily affecting the apocrine-bearing skin. Bowen disease is an intraepithelial squamous cell carcinoma having the potential to become invasive carcinoma. The histopathological concomitant features between EMPD and Bowen disease have been described. One theory is that primary EMPD arises multicentrically, within the epidermis from the pluripotent stem cells. Herein, we describe a case of EMPD that had bowenoid features, and review the previous cases associated with the origin of EMPD.

Trichorhinophalangeal Syndrome with Rapidly Progressive Childhood Male Pattern Baldness / 대한피부과학회지

No abstract available.

Pseudoxanthoma Elasticum Accompanied with Vitamin K-dependent Coagulation Factor Deficiency / 대한피부과학회지

Pseudoxanthoma elasticum is a multiorgan disorder, characterized by ectopic mineralization of elastic fibers of skin, eyes, and cardiovascular system. The dermatologic manifestations include laxity of skin, as well as cutis laxa-like wrinkling especially on both axillae. The classic forms of pseudoxanthoma elasticum are due to mutations in the ATP-binding cassette subfamily C member 6 (ABCC6) gene, a presumed transmembrane transporter expressed primarily in the liver and the kidneys. Recent case reports of mutations of gamma-glutamyl carboxylase (GGCX) gene describe associations with vitamin K-dependent coagulation factor deficiency and pseudoxanthoma elasticum as well. A 23-year old woman presented with laxity on both axillae and trunk and a history of vitamin K-dependent coagulation factor deficiency, diagnosed 2 years ago. Fragmented and markedly degenerated elastic fibers with calcium deposition were identified on biopsy specimens. Herein, we report a case of autosomal recessive pseudoxanthoma elasticum combined with vitamin K-dependent coagulation factor deficiency.

Bilateral Collagenous Fibroma Occurred on Both Anterior Superior Iliac Spine / 대한피부과학회지

Collagenous fibroma is a recently described rare benign tumor that mainly affects those in the fifth through seventh decades. It is a painless solitary mass, which grows slowly for more than 6 months, up to 20 cm. Several cases were reported chromosomal rearrangements with a breakpoint at 11q12. Histopathologically, it shows well-circumscribed mass that consists of scattered stellate cells in hypovascular collagenous matrix without atypia or mitosis. Management method is excision with functional preservation. In Korea, only two cases of collagenous fibroma have been reported so far. A 69-year-old woman was presented to our clinic with two painless well-demarcated hard masses, 4.5x4.5 and 4.5x2.5 cm in size, on both anterior superior iliac spine. Traumatic injury or a previous event was not noticed by the patient. After histopathologic examination, those masses were diagnosed as collagenous fibroma.

Bilateral Collagenous Fibroma Occurred on Both Anterior Superior Iliac Spine / 대한피부과학회지

Collagenous fibroma is a recently described rare benign tumor that mainly affects those in the fifth through seventh decades. It is a painless solitary mass, which grows slowly for more than 6 months, up to 20 cm. Several cases were reported chromosomal rearrangements with a breakpoint at 11q12. Histopathologically, it shows well-circumscribed mass that consists of scattered stellate cells in hypovascular collagenous matrix without atypia or mitosis. Management method is excision with functional preservation. In Korea, only two cases of collagenous fibroma have been reported so far. A 69-year-old woman was presented to our clinic with two painless well-demarcated hard masses, 4.5x4.5 and 4.5x2.5 cm in size, on both anterior superior iliac spine. Traumatic injury or a previous event was not noticed by the patient. After histopathologic examination, those masses were diagnosed as collagenous fibroma.

Systematized Inflammatory Linear Verrucous Epidermal Nevus / 대한피부과학회지

Inflammatory linear verrucous epidermal nevi (ILVEN) were first described in the literature, in 1971, by Altman and Mehregan. Most cases were reported as solitary lesions. In contrast, systematized ILVEN, involving wide areas of the integument, has only rarely been reported. A variety of treatment modalities has been reported, ranging from topical medications, such as potent corticosteroids or tretinoin 0.1% to variable procedures, including CO2 and pulsed dye laser, cryotherapy, and surgical excision. However, multifocal skin lesion is more difficult to treat. An 8-year old boy was presented with an extensive thick scaly plaques and patches, affecting the trunk and the four extremities sparing face. It developed when he was 3 years old, and he complained pruritus. On physical examination, linear, or whirl-like scaly plaques were seen, along with Blaschko lines. Pathologic finding was in accordance to ILVEN. We treated him with topical calcipotriol, tacrolimus and systemic acitretin. After 8 months, the lesion and symptoms improved.

Large Dermal Non Neural Granular Cell Tumor on the Surgical Wound Site

Granular cell tumors (GCTs) can be divided into neural type with S-100 reactivity and non-neural type without that. The latter has not been widely recognized and there are only fewer reports available when compared to conventional GCT. A 65-year-old man was presented with the presence of a painless mass on his back. The mass had developed into a small nodule on the scar developed because of previous surgery carried out 2 years ago. The tumor consisted of large, polygonal cells comprising of an enormous number of faintly eosinophilic small granules in the cytoplasm. The cytoplasmic granules were stained positively for periodic acid-Schiff stain. Immunohistochemical stains for S-100 protein and neuron-specific enolase were found to be negative. Herein, we report the appearance of a very rare case of non neural GCT developed on the surgical scar in support with relevant literature reviews.

A Case of Familial Comedonal Darier's Disease

Darier's disease is a genetic disorder of keratinization with autosomal dominant inheritance. Its appearance is usually in the form of greasy, crusted, keratotic yellow-brown papules and plaques found particularly on seborrheic areas of the body. However, there are some clinical variants showing atypical skin lesions. Here we report an unusual case of Darier's disease, which mainly showed prominent comedonal papules over the face.

Recurrent Primary Cutaneous Adenoid Cystic Carcinoma along an Abdominal Surgical Scar after Repeated Simple Excisions / 대한피부과학회지

Primary cutaneous adenoid cystic carcinoma is a rare, slow-growing malignancy that consists of basaloid cells. It characteristically follows an indolent course but has a high tendency to recur locally after excision. We experienced a recurrent primary adenoid cystic carcinoma of the abdomen in a 69-year-old female. It had recurred locally three times over 13 years despite repeated excisions. Wide spreading and perineural invasion of tumor cells were identified during Mohs micrographic surgery, and it seemed to be related to the repeated recurrences. Herein, we report this rare case with clinical and histological features of a recurrent nature.

Non-familial Generalized Hypotrichosis Simplex / 대한피부과학회지

Hypotrichosis simplex is a descriptive term of hair loss without other ectodermal or systemic abnormalities. Hypotrichosis simplex with non-familial and generalized types has been seldom reported. A 30-year-old man visited our clinic complaining of scalp hair loss since birth. There was no hair on the arms, axillae and legs. He had relatively scanty eyebrows and pubic hairs. None of his family members had known health problems or any hereditary disease. Hair shaft examination based on electron microscopy did not reveal any structural abnormalities. Microscopic examination of a scalp biopsy specimen showed a reduced number of hair follicles with vellus hairs replacing terminal hairs. Herein we report a rare and interesting case of non-familial generalized hypotrichosis simplex.

Using a Subcutaneous Island Pedicle Flap and Periosteal Suspension Suture Following Mohs Surgery for Basal Cell Carcinoma Involving the Nose and Nasolabial Fold / 대한피부과학회지

Skin cancers usually occur on the face and so successive cutaneous reconstruction after surgery is very important for the patients' quality of life. Cutaneous reconstruction is especially difficult when the defects after surgery involve the nasolabial fold. The nasolabial folds run from each side of the nose to the corners of the mouth, separating the cheeks from the upper lip. This area has complex contours, unique skin color and texture and the limited availability of mobile adjacent skin. We reconstructed such a defect after Mohs micrographic surgery for basal cell carcinoma of the nasolabial fold area, and we used a subcutaneous island pedicle flap and periosteal suspension suture. Herein we report on the details with the pictures, and we discuss the cosmetic effect and limitations of this method.