Hematological indices in human immunodeficiency virus and pulmonary tuberculosis infections in parts of Delta State, Nigeria

To enhance the care and management of human immunodeficiency virus [HIV] and pulmonary tuberculosis [TB] positive patients, as part of an overall effort to reduce morbidity and mortality of HIV-related death in Nigeria. Hematological investigations were carried out on 205 patients suspected of HIV and/or TB, and 100 apparently healthy control subjects in Kwale, Agbor, and Eku in parts of Delta State, Nigeria from February 2006 to February 2008. World Health Organization systems 2 for HIV-1 and 2 antibodies screening technique was used for the screening of the subject's HIV status, Ziehl Nelson technique for TB, hematocrit, and Leishman staining techniques were used for full blood count determination. Our results showed that the mean packed cell volume obtained for infected subjects was statistically significant [p=0.0000074] when compared to the control subject's value. The mean neutrophil and eosinophil counts obtained were of specific disease diagnostic relevance when compared to the control group. The gender related distributions of hematological indices were compared with the control group. The study confirms the importance of full blood count in the monitoring and management of HIV and TB infections

Health point prevalence of human immunodeficiency virus and pulmonary tuberculosis among patients in various parts of Delta State, Nigeria

To assess the prevalence of human immunodeficiency virus [HIV] and pulmonary tuberculosis [PTB] in the study population in Delta State of Nigeria. Two hundred and five patients suspected of HIV and TB were prospectively studied in Kwale, Agbor and Eku in Delta State of Nigeria from February 2006 to February 2008. Human immunodeficiency virus status was determined using World Health Organization systems II, and Zeihl Nelson staining technique was used for TB screening. A health point prevalence rate of 53.2%, was obtained for HIV, 49.3% for TB, and 16.6% for HIV/TB. The population of HIV positive [p=0.890, p=0.011, p=0.006] and TB positive [p=0.135, p=0.0003, p=0.0001] subjects were statistically significant among the suspected subjects while the HIV/TB positive cases were not statistically significant [p=0.987, p=0.685, p=0.731]. Our study showed that HIV and PTB infections remains high in parts of Delta State in Nigeria