RESUMO
Paget's disease of the breast occurs almost exclusively in women, and is characterized by a unilateral, sharply defined eczematous skin lesion caused by epidermal metastases from underlying ductal adenocarcinoma of the breast. Paget's disease of the male breast is extremely rare. A 61-year-old patient had a skin lesion on the right nipple for 1 year. The lesion was a well defined, brownish, crusted, and keratotic papule, and was associated with an underlying walnut sized, fixed, hard mass and a palpable ipsilateral axillary lymph node. Histologic findings were consistent with Paget's disease. Results of immunoperoxidase staining technigues for S-100 protein and carcinoembryonic antigen were negative. After a modified radical mastectomy and chemotherapy, the patient has been in remission for 12 months.
Assuntos
Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Adenocarcinoma , Mama , Antígeno Carcinoembrionário , Tratamento Farmacológico , Juglans , Linfonodos , Mastectomia Radical Modificada , Metástase Neoplásica , Mamilos , Doença de Paget Mamária , Proteínas S100 , PeleRESUMO
Trichophyton verrucosum is a worldwide zoophilic dermatophye. The human infection was first reported in t.he South western part of Korea in 1986 and Fas been increasing in Taegu area. Thirty-one strains of T. verrucosum isolated from the patients in Taegu area were investigated for their mycological features. Gross observation on Sabot rauds dextrose agar, microscopic examination by scotch tape method and slide culture or Sabourauds dextrose agar and potato dextrose agar, and hair perforation test were perforn ed at 37C. The averages of the largest dimensions of the colonies were .9mm at 2 weeks and 59mm at 4 weeks. The morphologic features of the colonies were clasified into three types. Eighteen of 31 strains showed flatwhitish, disc-like colonies with suvmerging hyphae, 11 strains had large radiating follows on the center of the colonies, and 2 strains showed colonies having diffuse fine folds on their surfaces with well-defined borders. On microscopic exaniination, many chlamydospores, antlerlive hyphae, oval and clavate microconidia, and rat tail or string bean shaped macroconidia were observed. It seemed that observation on potato dextrose agar during 10 to 14 days af er inoculation was suitable method for microscopic examination of T. verrucosum. All 31 strains showed positive reaction on hair perforation test.
Assuntos
Animais , Humanos , Ratos , Ágar , Glucose , Cabelo , Hifas , Coreia (Geográfico) , Solanum tuberosum , Cauda , TrichophytonRESUMO
We report a case of piroxicam-induced photosensitive dermatitis in a 54-year-old female. She had taken oral piroxicam and was exposed to the sunlight on her way home for a few minutes. Several hours after the sun-exposure she developed well-defined, confluent, erythematous plaques and numerous vesicobullae with pruritus and prickling sensation on the sun-exposed areas. A phototest was done on her first visit. The minimal erythemogenic dose (2 J/cm²) of ultraviolet (UV) A was markedly decreased whereas that of UVB was within a normal limit. Visible light irradiation for 30 minutes did not cause skin lesions. Six months after the initial skin lesions, a photopatch test with 1% and 10% piroxicam solution followed by UVA (10 J/cm²) irradiation showed positive responses on both concentrations.
Assuntos
Feminino , Humanos , Pessoa de Meia-Idade , Dermatite , Luz , Piroxicam , Prurido , Sensação , Pele , Luz SolarRESUMO
A case of sporotrichosis misdiagnosed as lupus vulgaris was presented. A 56-year-old woman had been to pea sized, nontender pustules and a hypertrophic-scar-like nodule on the right thigh. She denied any trauma before the lesions developed. Histopathologic findings from the lesion showed tuberculosis-like granulomatous changes. And she was diagnosed as lupus vulgaris. She also had pulmonary tuberculosis and had been treated with antituberculous drugs for 1 year. But skin lesions was not cleared. We suspected the lesions as one of deep mycoses and could confirm sporotrichosis by mycologic studies. They showed characteristic gross colonies and microscopic findings of Sporothrix schenckii..