Leukonychia Striata Caused by Trichophyton Rubrum / 대한피부과학회지

The authors observed 5 cases with leukonychia striata caused by Trichophyton rubrum infection. They were 4 males and 1 female in the 28-32 years age group. In 4 of the 5 cases the lesions disappeared in 1-3 months with treatment-avulsion of the involved nails followed by oral griseofulvin 500mg/day, one case did not have follow-up observation.

Observation about Dapsone-Resistant Cases of Leprosy Partients by Clinical and Bacteriological Aspects / 대한피부과학회지

Fifteen hundred seventy-one leprosy patients registered in the leprosy Mission Hospital from Mar. 1957 to Sep. 1980 were investigated for dapsone resistance by clinical and bacteriological aspects. The results are as follows: There were 29 suspected dapsone-resistant cases out of a total 1571 registered leprosy patients (1. 85%), 26 of 650 of lepromatous type(4. 00%), and 3 of 164 of borderline type (l. 83%). In 1969, we observed the first case if suspected dapsone-resistant leprosy. Since then, suspected dapsone-resistant cases increased and we observed as many as 8 cases in 1977. But frequency of cases has decreased since 1978. (countinued..)

Tuberous Sclerosis Occuring through 3 Generations / 대한피부과학회지

Tuberous sclerosis is a complex neurocutaneous disease inherited as an autosomal dominant pattern, which is characterized by facial angio-fibroma, mental retardation and seizures. Many cases have been reported in the literatures, but familial cases are relatively rare. We present 9 cases of tuberous sclerois occuring througb 3 generations, which are 3 cases of angiofibroma, mental retardation and seizures, 2 cases of facial angiofibroma and seizures, 1 case of mental retardation and seizures and 3 cases who showed facial angiofibroma only. Two brothers in this family reveald icthyosis vulgaris without tuberous sclerosis.

Two Cases of Bullous Dermatitis Herpetiformis / 대한피부과학회지

Dermatitis herpetiformis occurs rarely in childhood and certain features of the disease in children differ from its manifestation in adults. The eruptions are commonly bullous, show little predilection for the typical regional pattern of the adults, may be nonpruritic, have a shorter course, and often are resistant to the usual therapy. A review of literature shows that in patients over 50 years of age or older the tendency is to manifecst predominantly, although not as strikingly for children, a vesicobullous type of dermatitis herpetiformis with large bullae, varying 1 to 5cm or more in diameter. The authors present two cases of bullous dermatitis herpetiformis confirmed by histology; the first case is a 5 year-old boy who has tense bullae, pustules, and pigmentations on the inguinal region, lower abdomen, buttocks, face, and extensor surfaces of the extremities of 1 yars duration; the second case is a 44 year old housewife who has eruptions of vesicles, bullae, and erosion on the buttccks, back, abdomen, ext;remities, oral cavity, and vulva of 15 days' duration. The authors reviewed the relevant literature and discussed the clinicaI feat ures of both cases thoroughly.