A Case of Esophageal Submucosal Gland Duct Adenoma / 대한내과학회지

An esophageal submucosal gland duct adenoma is a rare benign disease. We report a 58-year-old man who presented with an esophageal submucosal tumor on health screening endoscopy. The endoscopic examination showed a round elevated lesion with central depression at the mid-esophagus. On endoscopic ultrasonography, an anechoic lesion with some hyperechoic septal structures measuring 8 mm in the largest diameter was observed in the third layer. We resected the lesion endoscopically. Histologically, there were several dilated gland ducts, with proliferation of the inner epithelial and outer myoepithelial cell layers. These findings were compatible with a submucosal gland duct adenoma of the esophagus.

Allopurinol hypersensitivity syndrome and pure red cell aplasia associated with allopurinol treatment / 대한내과학회지

Allopurinol is widely used to reduce serum uric acid levels and, generally, has mild side effects. Rarely, allopurinol hypersensitivity syndrome occurs and this consists of severe systemic skin lesions, fever, reduced kidney and liver function, and leukocytosis with eosinophilia. Extremely rarely, allopurinol-induced pure red cell aplasia is reported. We report a case of allopurinol hypersensitivity syndrome and pure red cell aplasia following allopurinol therapy for eight weeks and the disease response to steroid therapy in a patient with chronic renal insufficiency.

A case of typhoid fever with manifestations of acute hepatitis / 대한내과학회지

Typhoid fever is a febrile illness with a variety of systemic manifestations; however, icteric typhoid hepatitis, mimicking the clinical features of acute hepatitis, is very uncommon. A 45-year-old man was admitted to the hospital for evaluation of fever, dark-colored urine, and jaundice. On admission, the total bilirubin was 4.3 mg/dL, and the AST and ALT were 468 and 319 IU/L, respectively. Salmonella typhi was identified by blood culture. A liver biopsy revealed some mononuclear cell infiltrations without hepatocyte necrosis or typhoid nodules. CT scan findings showed splenomegaly and mesenteric lymphadenopathy. With the administration of ceftriaxone, he became afebrile and showed improvement in the jaundice, with normalization of AST and ALT.

Effect of Preoperative Sonographic Venous Mapping on Formation of Vascular Access / 대한신장학회지

PURPOSE: Active venous mapping by ultrasonography much increased the rate of autologous graft operations while significantly decreasing the rate of maturation failures. Reports on this phenomenon, however, have been rare in Korea. We here the effect of venous mapping by ultrasonography. METHODS: From 2005.1 to 2006.6, we selected 73 patients with autologous or artificial vessel or tunneled catheter and put them into 2 groups: the group that had operation after venous mapping by ultrasonography (n=40) and the control group (n=33) and rate of autologous vessels and the frequency and cause of maturation failure were analysed retrospectively. RESULTS: Patient's age, patient ratio of age, DM ratio in the map group against the control group were respectively 58.95+/-19.93 (25-86) vs 60.76+/-11.93 (39-80), 20/40 vs 17/33, 14/40 vs 19/33 showing no signficant differences between them. Gender ratios (M/F) were 12/28 vs 21/12 showing more females in the mapping group. As for the rate of autologous vessel, 34 out of 40 in map group, and 31 out of 33 in the control group showed no significant difference. After the first operation, 36 out of 40 in map group and 16 out of 33 in the control group were using autologous vessel. The map group had tendency to use higher rate of autologous vessels than the control group (p=0.059). MF ratio was significantly low in the mapping group (p=0.000). CONCLUSION: Carrying out preoperative venous mapping would promote development of appropriate techniques, together with increased use of autologous vessels. It is also thought that MF reduced the chance of reoperation.

A Case of IgA Nephropathy Associated with Acute Myeloid Leukemia / 대한신장학회잡지

The incidence of glomerulonephritis associated with malignancy is not common. Membranous glomerulonephritis associated with carcinomas and minimal change nephrotic syndrome with Hodgkin's disease has been occasionally reported. The pathogenesis of glomerular injury associated with malignancy is not well known. The IgA nephropathy associated with malignancy, though rare, has been reported. IgA nephropathy associated with acute myeloid leukemia, however, is yet to be reported. We hereby report a case of IgA nephropathy associated with acute myeloid leukemia (AML M2).

A Case of IgA Nephropathy Associated with Acute Myeloid Leukemia / 대한신장학회잡지

The incidence of glomerulonephritis associated with malignancy is not common. Membranous glomerulonephritis associated with carcinomas and minimal change nephrotic syndrome with Hodgkin's disease has been occasionally reported. The pathogenesis of glomerular injury associated with malignancy is not well known. The IgA nephropathy associated with malignancy, though rare, has been reported. IgA nephropathy associated with acute myeloid leukemia, however, is yet to be reported. We hereby report a case of IgA nephropathy associated with acute myeloid leukemia (AML M2).