RESUMO
Multiple sclerosis (MS) is an immune-mediated, inflammatory demyelinating disease of the central nervous system. The coexistence of multiple sclerosis and rheumatoid arthritis is very rare. This rare association is interesting due to the overlapping pathophysiological similarities of T-cells and tumor necrosis factor-alpha (TNF-alpha) in both diseases. We report a case of a Korean 10 year old girl with multiple sclerosis, who after 3 years developed a clinical and serological manifestation of juvenile rheumatoid arthritis.
Assuntos
Humanos , Artrite Juvenil , Artrite Reumatoide , Sistema Nervoso Central , Doenças Desmielinizantes , Esclerose Múltipla , Esclerose , Linfócitos T , Fator de Necrose Tumoral alfaRESUMO
We describe a case of Streptococcus pyogenes pneumonia in a 63-year-old man presenting with rhabdomyolysis and acute renal failure. The patient completely recovered following treatment with mechanical ventilation, continuous venovenous hemodiafiltration, and intravenous antimicrobial agents.
Assuntos
Humanos , Pessoa de Meia-Idade , Injúria Renal Aguda , Anti-Infecciosos , Hemodiafiltração , Pneumonia , Respiração Artificial , Rabdomiólise , Streptococcus pyogenes , StreptococcusRESUMO
Pyogenic sacroiliits is a rare disease and the diagnosis is difficult because of unawareness of the disease and nonspecific symptoms and signs mimicking septic hip, iliopsoas muscle abscess and herniation of intervertebral disk. There are some predisposing factors related to the disease like trauma, pregnancy, intravenous drug abuse and infection of other systems such as skin, genitourinary system and heart. Staphylococcus aureus is the most common causative bacteria. Here we describe a case of 27-year-old woman presented with acute onset of back and left buttock pain. Bone scintigraphy revealed increased uptake at left sacroiliac joint and computed tomography of the pelvis showed left sacroiliitis with left iliacus and iliopsoas abscess. There was no history of usual predisposing conditions. S. aureus was grown from blood cultures and the patient improved with 2 weeks of intravenous cefazolin followed by 4 weeks of oral clindamycin treatment.
Assuntos
Adulto , Feminino , Humanos , Gravidez , Abscesso , Bactérias , Nádegas , Causalidade , Cefazolina , Clindamicina , Diagnóstico , Coração , Quadril , Disco Intervertebral , Pelve , Abscesso do Psoas , Cintilografia , Doenças Raras , Articulação Sacroilíaca , Sacroileíte , Pele , Staphylococcus aureus , Staphylococcus , Abuso de Substâncias por Via Intravenosa , Sistema UrogenitalRESUMO
We describe a case of Streptococcus pyogenes pneumonia in a 63-year-old man presenting with rhabdomyolysis and acute renal failure. The patient completely recovered following treatment with mechanical ventilation, continuous venovenous hemodiafiltration, and intravenous antimicrobial agents.
Assuntos
Humanos , Pessoa de Meia-Idade , Injúria Renal Aguda , Anti-Infecciosos , Hemodiafiltração , Pneumonia , Respiração Artificial , Rabdomiólise , Streptococcus pyogenes , StreptococcusRESUMO
Pyogenic sacroiliits is a rare disease and the diagnosis is difficult because of unawareness of the disease and nonspecific symptoms and signs mimicking septic hip, iliopsoas muscle abscess and herniation of intervertebral disk. There are some predisposing factors related to the disease like trauma, pregnancy, intravenous drug abuse and infection of other systems such as skin, genitourinary system and heart. Staphylococcus aureus is the most common causative bacteria. Here we describe a case of 27-year-old woman presented with acute onset of back and left buttock pain. Bone scintigraphy revealed increased uptake at left sacroiliac joint and computed tomography of the pelvis showed left sacroiliitis with left iliacus and iliopsoas abscess. There was no history of usual predisposing conditions. S. aureus was grown from blood cultures and the patient improved with 2 weeks of intravenous cefazolin followed by 4 weeks of oral clindamycin treatment.
Assuntos
Adulto , Feminino , Humanos , Gravidez , Abscesso , Bactérias , Nádegas , Causalidade , Cefazolina , Clindamicina , Diagnóstico , Coração , Quadril , Disco Intervertebral , Pelve , Abscesso do Psoas , Cintilografia , Doenças Raras , Articulação Sacroilíaca , Sacroileíte , Pele , Staphylococcus aureus , Staphylococcus , Abuso de Substâncias por Via Intravenosa , Sistema UrogenitalRESUMO
Henoch-Sch?nlein purpura (HSP) is a systemic vasculitis with IgA dominant immune complex deposits that affect the small vessels in the skin, joints, gastrointestinal tract and kidneys. Gastrointestinal symptoms are common and the manifestations include abdominal pain, bleeding, bowel infarction, intussusceptions or even perforation. Polyarticular onset juvenile rheumatoid arthritis (JRA) is a rare form of arthritis that affects children and young adults. The relationship between HSP and JRA is uncertain. We report on a 24-year-old man with a history of polyarticular onset JRA and HSP that was complicated by hemorrhagic gastroenteritis. The gastroscopy and colonoscopic findings showed extensive hemorrhagic inflammatory changes of the gastric and intestinal mucosa. The patient had severe bloody diarrheal symptoms, abdominal pain and gross hematuria. The 24 hours urine chemistry profile showed the proteinuria was greater than 4.5 g/day, and immunofluorescent staining of the renal biopsy specimen showed diffuse granular mesangial deposits of IgA and C3. The abdominal manifestations and proteinuria were improved after methylprednisolone therapy.