Immune Reconstitution Inflammatory Syndrome in CNS Tuberculosis.

Background: Immune Reconstitution Inflammatory Syndrome (IRIS), an exaggerated inflammatory response with clinical worsening due to immune recovery during treatment, is rare in the immune-competent population. Case characteristics: A 5-½-year old immunecompetent girl with CNS tuberculosis without HIV who developed paradoxical IRIS. Outcome: Response to supportive care along with Anti-tuberculosis treatment. Message: IRIS can occur in tuberculosis, even in the immuno-competent.