Effect of Shoulder Abduction Angles on EMG Activity of the Abdominal Muscles during Single Leg Holding on the Foam Roller

Purpose@#This study examined the electromyography (EMG) activity of the abdominal muscles and the ratio of the oblique abdominal muscle activity to the rectus abdominis muscle during a single-leg holding position with isometric shoulder abduction (SLHISA) in the supine position on a foam roller. @*Methods@#Nineteen healthy males were recruited to the study. Each subject was asked to lay on a round foam roller and perform single-leg (nondominant) holding with contralateral shoulder abduction to one of three angles (45°, 90°, or 135°) in random order. The surface EMG signals of the bilateral rectus abdominis (RA), external oblique abdominis (EO), and combined internal oblique abdominis (IO) and transverse abdominis (TrA) muscle were collected during the tasks. The EO/RA and (IO & TrA)/RA ratios were determined using surface EMG. One way repeated measure ANOVA with three SLHISAs was used to assess the significant abdominal muscle EMG activity and the ratio of the oblique abdominal muscles activity to the RA muscle. The statistical significance level was p<0.05. @*Results@#The results were as follows. The SLHISA 135° showed significantly higher EMG activity of both RAs, left EO, and right IO & TrA muscles (p<0.05). The right EO and left IO and TrA muscles/RA were significantly different among the SLHISA angles. The SLHISA 45° showed a significantly greater ratio of right EO/RA and left IO & TrA/RA (p<0.05). @*Conclusion@#SLHISA on a foam roller is useful for lumbopelvic stabilization exercise by increasing the activity and recruiting a specific pattern of the oblique abdominal muscle.

Effect of Shoulder Abduction Angles on EMG Activity of the Abdominal Muscles during Single Leg Holding on the Foam Roller

Purpose@#This study examined the electromyography (EMG) activity of the abdominal muscles and the ratio of the oblique abdominal muscle activity to the rectus abdominis muscle during a single-leg holding position with isometric shoulder abduction (SLHISA) in the supine position on a foam roller. @*Methods@#Nineteen healthy males were recruited to the study. Each subject was asked to lay on a round foam roller and perform single-leg (nondominant) holding with contralateral shoulder abduction to one of three angles (45°, 90°, or 135°) in random order. The surface EMG signals of the bilateral rectus abdominis (RA), external oblique abdominis (EO), and combined internal oblique abdominis (IO) and transverse abdominis (TrA) muscle were collected during the tasks. The EO/RA and (IO & TrA)/RA ratios were determined using surface EMG. One way repeated measure ANOVA with three SLHISAs was used to assess the significant abdominal muscle EMG activity and the ratio of the oblique abdominal muscles activity to the RA muscle. The statistical significance level was p<0.05. @*Results@#The results were as follows. The SLHISA 135° showed significantly higher EMG activity of both RAs, left EO, and right IO & TrA muscles (p<0.05). The right EO and left IO and TrA muscles/RA were significantly different among the SLHISA angles. The SLHISA 45° showed a significantly greater ratio of right EO/RA and left IO & TrA/RA (p<0.05). @*Conclusion@#SLHISA on a foam roller is useful for lumbopelvic stabilization exercise by increasing the activity and recruiting a specific pattern of the oblique abdominal muscle.

Analysis of Perception and Satisfaction of Military Foodservice that are Provided According to the Ranks of the Soldiers / 대한지역사회영양학회지

OBJECTIVES: The purpose of this study is to provide the basic data for efficient operation and management of the military foodservice by analyzing the satisfaction of the quality of the foodservice and the perception of the military foodservice which are provided according to the ranks of the soldiers. METHODS: A total of 252 military personnel (48 Private, 87 Private first class, 74 Corporal and 43 Sergeant) participated in Gyeonggi area from November 1 to 30, 2013, and data were analyzed by the SPSS Win (ver 18.0). RESULTS: The perception with foodservice, variety of menu (p < 0.001), importance (p < 0.01), problem (p < 0.05) and leftover reason (p < 0.05) significantly differed by the rank of the soldiers. With regard to the satisfaction with food, there were significant difference by rank for all items (p < 0.01). Satisfaction with facilities did not indicate significant differences by rank. Satisfaction with sanitation indicated significant difference by rank in the categories of table ware (p < 0.05), process of distribution (p < 0.05), employee's uniform (p < 0.001) and drinking water (p < 0.05). Satisfaction with service indicated significant difference by rank with regard to kindness of employees (p < 0.01), providing information on foodservice (p < 0.05) and fast distribution (p < 0.01). CONCLUSIONS: In order to improve the satisfaction of all ranks, there is a need to offer a variety of nutritionally balanced menu and a proper amount of food provided through the voluntary food distribution services. The results also suggested the need to find a sustainable foodservice management plan to carry out satisfaction surveys regularly in the military foodservice.

The Clinical Effectiveness of Open Septorhinoplasty for Primary Treatment of Nasal bone Fracture

BACKGROUND AND OBJECTIVES: Closed reduction has been a primary treatment procedure for nasal bone fracture, but the post-operative results have not always been satisfactory. We compared the satisfaction rate of closed reduction with that of open septorhinoplasty for the treatment of nasal bone fracture and evaluated the effectiveness of open septorhinoplasty for the primary treatment of nasal bone fracture. MATERIALS AND METHOD: We performed a retrospective review of patients who underwent a closed reduction treatment for nasal bone fracture from March 2004 to February 2006 and conducted telephone surveys to monitor their post-operative cosmetic and functional problems. We estimated the factors that were involved in the low satisfaction rate and determined the indications of open septorhinoplasty. Prospectively, the patients who underwent open septorhinoplasty from September 2006 to August 2007 were interviewed for their cosmetic and functional satisfaction rate. RESULTS: Forty percent of the patients who underwent closed reduction had cosmetic concerns and twenty percent had functional concerns. The factors involved in the low satisfaction rate were septal fracture, associated fractures, and multiple fragmentation. Eight percent of the patients who underwent open septorhinoplasty had cosmetic concerns and other eight percent had functional concerns. CONCLUSION: A careful pre-operative evaluation of the type of fracture is important for the treatment of nasal bone fracture. Also, when nasal bone fracture is combined with septal fracture, associated fracture or unilateral fragmentation, open septorhinoplasty has to be considered to reduce secondary deformities and to improve the satisfaction rate of the patients.

The Clinical Application of Endoscopic Sphenoidotomy and Anatomical Role of the Superior Turbinate

BACKGROUND AND OBJECTIVES: Recently, endoscopic sinus surgery (ESS) is commonly performed to treat the sphenoid sinus disease. Identification of the natural ostium of sphenoid sinus (SS) according to surgeon's operating view play an important role in endoscopic sphenoid approach. This study is undertaken to investigate the role of superior turbinate (ST) as an anatomic landmark of natural ostium of SS in endoscopic sphenoidotomy. MATERIALS AND METHODS: Medical records and computed tomography (CT) images of 77 patients from March 2006 to December 2007 who underwent ESS were analyzed. We tried to investigate the location and distance of the natural ostium on the superior turbinate, skull base and nasal septum. We also measured the anterior wall thickness of the SS by using CT images. RESULTS: The natural ostium of the SS was located on the medial side of the ST in all patients who underwent endoscopic sphenoidotomy (45 cases). The level of posteroinferior end of the ST corresponded to the inferior portion of anterior wall of the SS. The lateral portion thickness of the anterior wall of the SS was thinner than the medial portion (77 cases). CONCLUSION: During an endoscopic sphenoidotomy, the superior turbinate is an important anatomic landmark for identifying the natural ostium of the SS. When widening the anterior wall of SS is performed, we sug-gest that the procedure should be directed to the lateral 1/3 portion, considering the thickness of anterior wall of SS.

A Case of Diffuse Intracapsular Hemorrhage of Thyroid Gland after Fine Needle Aspiration Biopsy / 대한이비인후과학회지

Fine-needle aspiration biopsy (FNAB) is a safe, simple, repeatable and cost-effective method, and has excellent sensitivity and specificity. Thus, it is generally used as a primary study for the diseases of salivary gland, thyroid gland, and cervical lymph node in the head and neck area. FNAB has a small number of contraindications and complications, but most of the complications are minor complications. However, uncommon complications had been reported in the literature. In this report, we describe a 63 yearold woman who experienced dyspnea caused by diffuse intracapsular hemorrhage of thyroid gland after FNAB.

The Effect of Combination Therapy with Radiation and Selective Cyclooxygenase-2 Inhibitor on Xenografted Human Oral Cavity Squamous Cell Carcinoma in Nude Mice / 대한이비인후과학회지

BACKGROUND AND OBJECTIVES: It is known that tumor cells over-expressing COX-2 have resistance to many anticancer treatments. Among those treatments, along with surgery and chemotherapy, radiation therapy plays a significant role in the treatment of head and neck cancer. However, radiosensitivity of each cancer varies according to cancer types. Especially, the cancer over-expressing COX-2 is reported to have higher radioresistance to radiation therapy. The purpose of this study is to evaluate the effect of selective COX-2 inhibitor when combined with the radiation therapy, and to assess the possibility of clinical application of the selective COX-2 inhibitor for radiation therapy in the head and neck cancer. MATERIALS AND METHOD: The human oral cavity squamous carcinoma cells were cultured and xenografted in 40 athymic nude mice (1 x 10(7), left thigh, subcutaneous injection) and the mice were divided into 4 groups: the control group (10 mice), the radiation therapy group (10 mice, Group A), the Meloxicam injection group (10 mice, Group B), and the combination therapy group with radiation and Meloxicam (10 mice, Group C). The tumor volume was measured on every five days during the treatment and the tumor specimen was taken for immunohistochemical staining when the treatment was finished. The mean tumor volume, the apoptosis index and the proliferation index were measured. RESULTS: In the combination therapy group (Group C), the tumor growth rate was decreased compared to the radiation therapy group (Group A). Also, according to the result of the apoptosis index and the proliferation index measured using immunohistochemical staining, the combination therapy group presented a higher apoptosis index but a lower proliferation index than other groups. CONCLUSION: Meloxicam, selective COX-2 inhibitor, improves the efficacy of the radiation therapy for the human oral cavity squamous carcinoma and this effect was due to apoptosis modulation by selective COX-2 inhibitor.

Parathyroid Cyst: A Case Report / 대한이비인후과학회지

Cysts of the neck may present themselves as thyroid cysts, parathyroid cysts, thyroglossal duct cysts or branchial cleft cysts. Among them, parathyroid cysts are rare in clinical practice. They are usually observed in lower portion of the neck and rarely in the mediastinum or thymus. They are classified either as functioning or non-functioning. In this report, we describe a 49-year old man, with normal thyroid function and normal serum calcium level, presenting mass in the lower left third of the neck. Ultrasonography and computer tomography showed a well defined cystic lesion from the left lower pole of the thyroid to the supraclavicular area, which compressed and displaced the trachea to the right side. Fine needle aspiration of the cyst showed crystalclear watery fluid collection. After aspiration, cysts decreased in size, but the size increased again after a few days later. The patient was operated to remove the cyst and the left thyroid lobe. With the pathological study & analyzation of the cystic fluid for PTH level, the final diagnosis confirmed it as parathyroid cyst.

A Case of Subactue Maxillary Sinusitis due to Dental Material / 대한이비인후과학회지

Although chronic sinusitis is more often caused by the blockage of sinus ostia or the presence of an oroantral fistula, the disease is generally caused by dental problems. Although chronic maxillary sinusitis of dental origin is a rare entity when compared to sinus diseases of rhinogenic origin, it is extremely important to identify a dental etiology when it occurs. Chronic maxillary sinusitis of dental origin may be caused by the followings; chronic oroantral fistula (OAF), foreign bodies (dental fillings, teeth roots, parts of broken instruments, or packing materials) pushed through the root canal or OAF into the sinus, periapical granulomas or small inflammatory cysts of the molars and bicuspids, or large odontogenic cysts occupying total or subtotal space of the maxillary sinus. We report a case of unilateral subacute maxillary sinusitis associated with foreign body in the maxillary sinus. The foreign body in the maxillary sinus was dental Nu gauze. Dental Nu gauze helps to control bleeding and prevent pooling of wound fluid. Although endoscopic approach to chronic maxillary sinusitis of dental origin is a new, reliable method associated with less morbidity and lower incidence of complications, the operation was conducted mainly according to the Caldwell-Luc's method. Based on the findings of our case, we suggest that patient's dental problem history and dental state must be taken into consideration in cases where maxillary sinusitis is suspected.

2 Cases of Adenoid Cystic Carcinoma of the External Auditory Canal / 대한이비인후과학회지

Adenoid cystic carcinoma (ACC) is rare malignant tumor that affects major and minor salivary gland, ceruminous glands, and occasionally excretory gland of the female genital tract. While ACC accounts for less than 1% of all head and neck malignancies and approximately 10% of all salivary neoplasm, this tumor is one of the most common malignancies of the submandibular and minor salivary glands. ACC is characterized by a slow rate of progression, a tendency for perineural invasion, and a high recurrence rate after intensive surgery and adjuvant radiotherapy. ACC is divided into 3 types according to a distinctive histologic pattern. It is well known that the histologic pattern of ACC correlates well with the grade of tumors and prognosis. There are no clear guidelines for the treatment of ACC, but recently a combination of surgery and postoperative radiotherapy has been recommended. The most significant prognostic factors are clinical stage and distant metastasis. We present two cases of ACC arising from external auditory canal with a review of literature.

A Case of Advanced Gastric Cancer with Virchow's Node and Lung Metastasis Successfully Resected after Combined Chemotherapy of Taxotere, CDDP, and 5-FU

We report a case of advanced gastric cancer with Virchow's node and lung metastasis that responded remarkably to preoperative chemotherapy. A 47-year-old female patient was diagnosed as having incurable advanced gastric cancer with Virchow's node and multiple lung metastasis. Preoperative chemotherapy with Taxotere, CDDP and 5FU was carried out. After four courses of the regimen, the Virchow's node and the lung metastasis had disappeared, and a marked reduction of the gastric lesion was observed on the CT scan. Consequently, the patient underwent a total gastrectomy with D2 lymph node dissection. On histopathological examination, cancer cells were found to have infiltrated up to the muscle layer of the gastric wall, and 42 out of 60 resected lymph nodes were found to be metastatic. The patient received another two courses of chemotherapy after the operation

Effects of Noradrenaline on the Membrane Potential of Prostatic Neuroendocrine Cells of Rat

The prostate gland contains numerous neuroendocrine cells that are believed to influence the function of the prostate gland. Our recent study demonstrated the expression of both alpha 1- and alpha 2-ARs, signaling the release of stored Ca2+ and the inhibition of N-type Ca2+ channels, respectively, in rat prostate neuroendocrine cells (RPNECs). In this study, the effects of NA on the resting membrane potential (RMP) of RPNECs were investigated using a whole-cell patch clamp method. Fresh RPNECs were dissociated from the ventral lobe of rat prostate and identified from its characteristic shape; round or oval shape with dark cytoplasm. Under zero-current clamp conditions with KCl pipette solution, the resting membrane potential (RMP) of RPNECs was between 35 mV and 85 mV. In those RPNECs with relatively hyperpolarized RMP ( 45 mV) showed a transient hyperpolarization and subsequent fluctuation at around 40 mV on application of NA. Under voltage clamp conditions (holding voltage, 40 mV) with CsCl pipette solution, NA evoked a slight inward current (< 20 pA). NA induced a sharp increase of cytosolic Ca2+ concentration ([Ca2+]c), measured by the fura-2 fluorescence, and the voltage clamp study showed the presence of charybdotoxin-sensitive Ca2+ -activated K+ currents. In summary, adrenergic stimulation induced either depolarization or hyperpolarization of RPNECs, depending on the initial level of RMP. The inward current evoked by NA and the Ca2+ -activated K+ current might partly explain the depolarization and hyperpolarization, respectively.

The Regeneration Effect of Platelet-Rich Plasma on the Treatment of Grade II Furcation Involvement Using Synthetic Bone in Human / 대한치주과학회지

The present study evaluated of regeneration effect of platelet rich plasma on the treatment of grade II furcation involvement, with coralline calcium phosphate bone in humans. 30 teeth with grade II furcation defect were selected and 15 teeth(control) were treated with coralline calcium phosphate bone, the others(test) were treated with coralline calcium phosphate bone and platelet rich plasma. Pocket depth, clinical attachment level, width of keratinized gingiva width were measured at baseline, postoperative 3, 6months. from cementoenamel junction to alveolar crest and fundus were measured at baseline, 6months(re-entry). Both groups were statistically analyzed by Wilcoxon signed Ranks Test & Mann-whitney Test using SPSS program(5% significance level). The results were as follows: 1. Pocket depth, clinical attachment level, keratinized gingva width, cementoenamel junction - alveolar crest, cementoenamel junction - fundus were not differ significantly in both groups at baseline 2. The change of pocket depth, clinical attachment level, keratinized gingva width, cementoenamel junction - alveolar crest, cementoenamel junction - fundus in both groups were decreased significantly at 3, 6months(p<0.05). 3. The change of pocket depth, clinical attachment level in test group decreased significantly than control at 3, 6months(p<0.05) 4. The change of keratinized gingiva width, cementoenamel junction - alveolar crest, cementoenamel junction - fundus were not differ significantly in both groups at 3, 6months. 5. The pocket depth, clinical attachment level, keratinized gingiva width exhibited marked changes at 3 months in both groups. In conclusion, the results of this study suggest that platelet rich plasma have adjunctive clinical treatment effect to periodontal regeneration in grade II furcation defects.

Prognostic Implication of MDR1 (Multidrug Resistance) Gene Expression in Childhood Acute Leukemia / 대한혈액학회지

BACKGROUND: The most important mechanism of drug resistance is related to the over-expression of P-glycoprotein which is encoded by the MDR1 gene. The expression of MDR1 and its clinical implication in childhood leukemias has not been extensively assessed. METHODS: To evaluate the expression of MDR1 gene and its prognostic implication on the remission induction rate, relapse rate and survival, we assayed mdr1 mRNA by reverse-transcriptase polymerase chain reaction (RT-PCR) from bone marrow samples of 23 childhood ALL and 17 AML patients. The prognostic factors were analyzed by logistic regression and Cox proportional hazards model. RESULTS: mdr1 mRNA was expressed in 51.5% of patients at diagnosis. MDR1 status did not influence the remission induction rate both in ALL and AML. The relapse rate was significantly higher in MDR1 positive patients than in negative patients (29.4% vs. 0.0%, p=0.04). The cumulative relapse probability at 2 year was 60% vs 0% according to MDR1 status (p=0.006), suggesting the importance of MDR1 in the mechanism of relapse for childhood leukemias. The Kaplan-Meier 3-yr event-free survival (EFS) was 42.7% for MDR1 positive group, and 93.8% for negative patients (p=0.046). Analyses of prognostic factors showed that mdr1 mRNA expression was the sole prognostic factor predicting the poor EFS(X 2, 6.217; p=0.013). CONCLUSION: These results suggest that RT-PCR for mdr1 mRNA expression is a readily feasible and useful method of assessing multidrug resistance. The expression of MDR1 was found to be the most important prognostic factor predicting the possibility of relapse and EFS in patients with childhood leukemia.

Prognostic Implication of MDR1 (Multidrug Resistance) Gene Expression in Childhood Acute Leukemia / 대한혈액학회지

BACKGROUND: The most important mechanism of drug resistance is related to the overexpression of P-glycoprotein which is encoded by the MDR1 gene. The expression of MDR1 and its clinical implication in childhood leukemias has not been extensively assessed. METHODS: To evaluate the expression of MDR1 gene and its prognostic implication on the remission induction rate, relapse rate and survival, we assayed MDR1 mRNA by reverse-transcriptase polymerase chain reaction (RT-PCR) from bone marrow samples of 23 childhood ALL and 17 AML patients. The prognostic factors were analyzed by logistic regression and Cox proportional hazards model. RESULTS: mdr1 mRNA was expressed in 51.5% of patients at diagnosis. MDR1 status did not influence the remission induction rate both in ALL and AML. The relapse rate was significantly higher in MDR1 positive patients than in negative patients (29.4% vs. 0.0%, P= 0.04). The cumulative relapse probability at 2 year was 60% vs 0% according to MDR1 status (P=0.006), suggesting the importance of MDR1 in the mechanism of relapse for childhood leukemias. The Kaplan-Meier 3-yr event-free survival (EFS) was 42.7% for MDR1 positive group, and 93.8% for negative patients (P=0.046). Analyses of prognostic factors showed that mdr1 mRNA expression was the sole prognostic factor predicting the poor EFS (X2, 6.217; P=0.013). CONCLUSION: These results suggest that RT-PCR for mdr1 mRNA expression is a readily feasible and useful method of assessing multidrug resistance. The expression of MDR1 was found to be the most important prognostic factor predicting the possibility of relapse and EFS in patients with childhood leukemia.

Ectopic Paragonimiasis Presented as Multiple Colonic and Liver Masses

Ectopic paragonimiasis has been diagnosed in many organs such as the mesentery, ovary, pleura, central nervous system, subcutis and very rarely in the liver. However, simultaneous involvement of the colon and liver, which mimics colonic cancer with liver metastasis, is quite unusual, and to our knowledge has never been reported. Our case is a 63 year old woman who visited our hospital because of upper abdominal pain. Radiologically, space occupying lesions were detected in the transverse colon, mesocolon and left hepatic lobe. After the radical presection, they were proved to be an ectopic paragonimiasis forming multiple cavitary parasitic granulomas with Charcot-Leyden crystals and degenerating eggs.

The Results of Combined External Radiotherapy and Chemotherapyin the Management of Esophageal Cancer / 대한치료방사선과학회지

PURPOSE: To evaluate the role of combination therapy of external radiotherapy and chemotherapy in the management of advanced esophageal cancer as a primary treatment compared with radiation therapy alone. METHODS AND MATERIALS: A retrospective review of evaluable 55 esophageal cancer patients referredto the Department of Therapeutic Radiology, Paik Hospital for the external radiotherapy between Jul. 1983 and Dec.1994 was undertaken. Combined therapy patients (A group) were 30 and radiation alone patients (B group) were 25. Median age was 60 years old in A group(ranges : 42-81) and 65 years old in B group (ranges : 50-81). The male patients were 53. The fiffy patients had squamous cell carcinomas. Radiation doses of 2520-6480cGy were delivered over a period of 4-7weeks. using 4MV LIVAC. Chemotherapy was administered in bolus injection before, after, or during the course of external radiotherapy. The local control rate and patterns of failure according to both treatment modalities and 1,2 year survival rates according to prognostic factors (stage, tumor length, radiation dose etc.) were analysed. RESULTS: Median follow up period was 7 months (range : 2-73 months). Median survival was 7.5 months (20 days-29 months) in A group and 5 months(20 days-73 months) in B group. The 1,2 YSRs were 26.7%, 8.9% in A group. 12.7%, 4.3% in B group (p>0.05), respectively. The 1,2 YSRs according to stage(II/III), tumor length (5cm more or less). radiation dose(5000cGy more or less) of A and B group were analyzed and the differences of survival rates of both treatments were not statistically significant. But among group B, patients who received 5000cGy or more showed significant survival benefits (p<0.05). The treatment response rates of A and B group were 43.8%, 25.0%, respectively. Complete response rate of 25.0% in A and 8.3% in B were achieved. The local failure and distant metastsis were 52.4%, 23.8% in A group. 64.3%, 14.3% in B group, respectively. The combination therapy revealed more freguent leukopenia and nausea/vomiting than radiation alone group, but degree of side effects was only mild to modereate. CONCLUSION: The combined external radiotherapy and chemotherapy for advanced esophageal cancer appears to improve the response rate, local control rate and survival rate, but the improvement was not statistically significant. The side effects of combined modalities were mild to moderate without significant morbidity. Therefore it may be worthwhile to continue the present combined external radiotherapy and chemotherapy in the management of advanced esophageal cancer to confirm our result.

Effect of peripheral blood cell counts during remission induction and maintenance therapy on the prognosis and therapy of childhood acute lymphoblastic leukemia / 대한혈액학회지

No abstract available.

A case of 18q-syndrome / 대한주산의학회잡지

No abstract available.