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Objective:To construct a psychological support training program for palliative care specialist nurses based on positive psychology theory and make a preliminary application.Methods:From August to September, 2020, 142 palliative nursing specialist nurses in Hunan Provincial Palliative Nursing Specialist Training Base were selected as the research objects. Based on positive psychology therapy, using literature review and analysis, semi-structured interviews, expert group meetings and other methods to construct the program, and the work stress, psychological resilience and subjective well-being scores of nurses before and after 8 weeks of psychological support training were compared.Results:The program included three dimensions: cognition, emotion and behavior. After the psychological support training for 8 weeks, the nursing staff′s work stress score 80.76 ± 20.43 was lower than that before the psychological support training 84.70 ± 19.88, the difference was statistically significant( t=6.59, P<0.05), and the psychological resilience score 64.40 ±14.26 was higher than that before the psychological support training 60.19 ±15.85, the difference was statistically significant ( t=-7.39, P<0.05), and the subjective well-being score 75.70 ± 7.70 was higher than that before the psychological support training 74.13 ± 5.98, the difference was statistically significant ( t=-3.52, P<0.05). Conclusions:The psychological support training program based on positive psychology theory can reduce the the work stress, improve psychological resilience and increase subjective well-being of palliative care specialist nurses.
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Objective To explore the association of CT perfusion parameters to plasma levels of vascular endothelial growth factor (VEGF) and CD105 in patients with lung cancer to provide a reference for the treatment of patients with vascular targeting anti-selection.Methods Forty eight consecutive patients with diagnosed solitary pulmonary nodules underwent perfusion by 64-slice spiral CT.Among them,31 patients were diagnosed as lung cancers and 17 diagnosed as benign lesions.Statistical methods were used to analyze the differences of CT perfusion parameters [blood flow (BF),blood volume (BV),permeability surface (PS),and mean transit time (MTT)] between benign and malignant lesions,and to observe the correlation between cancer perfusion parameters and VEGF,and CD105.Results Compared to the group of benign lesions,the perfusion parameters BF,BV,and PS in the group of lung cancers were significandy higher than the group of benign lesions (P ＜ 0.05).MTT was not different between two groups (P ＞ 0.05).There were positive correlations between the expressions of VEGF or CD105 and perfusion parameters (BF,BV,and PS) of lung cancers.There were no correlation between perfusion parameter MTT and VEGF or CD105 (P ＞ 0.05).Conclusions CT perfusion parameters BF,BV,and PS can help in differentiating malignant from begin lesions.There is positive correlation between the perfusion parameters (BF,BV,and PS) and VEGF,and CD105 of lung cancers.It indicates that CT perfusion imaging is closely related to tumor angiogenesis,which may provide a non-invasive method to evaluate the blood supply.
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Objective To explore the effect of scanning time on CT perfusion (CTP) imaging quality and the accuracy of parameters in acute stroke patients.Methods CTP data of 30 patients with unilateral acute cerebral infarction were investigated retrospectively.CTP data with scanning times of 56 s,52 s,48 s,44 s,40 s and 36 s were analyzed for image postprocessing,the time density curves (TDCs) of the superior sagittal sinus (SSS),perfusion maps and the parameter values of ROI were obtained,and the first passage time of SSS was recorded.Results Compared with 56 s group,there was no significant difference of the image quality in the scanning time of 52 s group and 48 s group (both P＞0.05).The image quality was significantly negatively correlated with the first passage time of SSS in 52 s group,48 s group,44 s group,40 s group and 36 s group.Compared with 56 s group,there were significant differences in partial parameters of ROI when the scanning time was 44 s (all P＜0.05).Conclusion Decreasing whole-brain CTP scanning time reasonably can ensure the image quality and the accuracy of parameters and reduce the radiation dose.The whole-brain CTP with delay of 8 s,and scanning time of 48 s are recommended.
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Objective To explore the effect of scanning time on CT perfusion (CTP) imaging quality and the accuracy of parameters in acute stroke patients.Methods CTP data of 30 patients with unilateral acute cerebral infarction were investigated retrospectively.CTP data with scanning times of 56 s,52 s,48 s,44 s,40 s and 36 s were analyzed for image postprocessing,the time density curves (TDCs) of the superior sagittal sinus (SSS),perfusion maps and the parameter values of ROI were obtained,and the first passage time of SSS was recorded.Results Compared with 56 s group,there was no significant difference of the image quality in the scanning time of 52 s group and 48 s group (both P＞0.05).The image quality was significantly negatively correlated with the first passage time of SSS in 52 s group,48 s group,44 s group,40 s group and 36 s group.Compared with 56 s group,there were significant differences in partial parameters of ROI when the scanning time was 44 s (all P＜0.05).Conclusion Decreasing whole-brain CTP scanning time reasonably can ensure the image quality and the accuracy of parameters and reduce the radiation dose.The whole-brain CTP with delay of 8 s,and scanning time of 48 s are recommended.