Temporal variation of serum interleukin-37 and its relation with C-reactive protein in patients with acute ST-segment elevation myocardial infarction / 南方医科大学学报

<p><b>OBJECTIVE</b>To investigate the temporal changes of serum interleukin-37 (IL-37) concentration following acute ST-segment elevation myocardial infarction (ASTEMI) and the relationship between IL-37 and C-reactive protein (CRP) in patients with ASTEMI.</p><p><b>METHODS</b>This analysis was conducted in a cohort of 20 patients with an established diagnosis of ASTEMI and 26 patients admitted for chest pain but with normal findings in coronary angiography (control) between June 2012 and December 2013. Venous blood was collected at days 1, 3, 5, and 7 after myocardial infarction for measurement of serum IL-37 and CRP levels using enzyme-linked immunosorbent assay (ELISA).</p><p><b>RESULTS</b>Compared with the control group, the patients in ASTEMI group showed a significant acute elevation of IL-37 level on day 1 following myocardial infarction; IL-37 level reached the peak on day 3 and began to decrease on day 5, followed by a significant decrease on day 7. The time course of post-infarction CRP changes was consistent with that of IL-37 variations and showed a positive correlation the latter (r=0.63, P<0.05).</p><p><b>CONCLUSION</b>IL-37 may participate in the inflammatory responses in ASTEMI.</p>

Research in application of timing-work schedule mode in human resource management in the outpatiet department of island hospital / 中国实用护理杂志

Objective To evaluate the effectiveness of application of timing- work schedule mode in hu-man resource management according to the characteristc and work load of the outpatient department in island hospital. Methods General quality of care, nurses and patients' satisfaction degree were compared before and 12 months after the application of timing- work schedule. Results Total quality of care and nurses and pa- tients' satisfaction degree with nursing had statistical significance before and after the application of timing-work schedule mode. Conclusions To adoption of timing-work schedule mode in outpatient department in island hospital is feasible, it not only saves the nursing human resource, but also can guarantee the nursing quality and improve patients' satisfaction degree. So it is worthy of clinical application.

Effects of dexamethasone on iNOS in pulmonary tissues of rats during simulated weightlessness / 解放军医学杂志

Objective To investigate the effects of dexamethasone on inducible nitric oxide synthase (iNOS) in pulmonary tissues of tail-suspended rats simulating weightlessness. Methods Twenty Sprague-Dawley male rats were randomly divided into 2 groups: tail-suspended for 7 days (n=10) without treatment and dexamethasone treatment group (n=10). Tail-suspension was used to simulate weightlessness. The expression of iNOS in the pulmonary tissue was examined by Western blot and immunohistochemistry. Results The results showed that the level of iNOS in the pulmonary tissue of treatment group was decreased significantly(P

Effects of dexamethasone on cell apoptosis in pulmonary tissues in rats after tail-suspension simulating weightlessness / 解放军医学杂志

Objective To investigate the effects of dexamethasone on prevention of apoptosis in pulmonary tissues of rats after simulated weightlessness. Methods Tail suspension was used to simulate weightlessness. Thirty Sprague-Dawley male rats were divided randomly into 3 groups: control group, tail suspension for 7 days group, and dexamethasone treatment after suspension group. TUNEL technique was used to detect cell apoptosis in pulmonary tissues. Results The rate of apoptotic cells in the lung of rats suspended for 7 day was higher than that of control group(P

Investigatin on Clinical Effects of Astragalus Injection on Preventing Cisplatin Induced Early Kidney Injury / 中成药

0.05). But the determined values in the above two dose groups of Astragalus Injection were obviously lower than that in cisplatin group. There were remarkable differences.( P