Effects of Tamsulosin on Premature Ejaculation in Men with Benign Prostatic Hyperplasia

PURPOSE: Previous studies have revealed that tamsulosin is effective in improving lower urinary tract symptoms (LUTS) and erectile functioning but has some inhibitory effects on ejaculation, including decreased ejaculatory volume. However, these inhibitory effects on ejaculation can be beneficial to patients with premature ejaculation (PE). Therefore, this study was conducted to understand the effect of tamsulosin on PE in men with benign prostatic hyperplasia. MATERIALS AND METHODS: Twenty-nine patients who visited with LUTS were categorized into 2 groups of LUTS-only patients (n=12) and LUTS combined with PE (LUTS+PE) patients (n=17), and 0.4 mg of tamsulosin was administered to the patients of both groups for 12 weeks. Comparative analyses of before and after the treatment were conducted for calculating the International Prostate Symptom Score (IPSS), International Index of Erectile Function-5 (IIEF-5), intravaginal ejaculatory latency time (IELT), premature ejaculation diagnostic tool (PEDT), and premature ejaculation profile (PEP). The patients with an IPSS score of 8 or higher were determined as LUTS patients, and the patients with IELT of less than 2 minutess and a PEDT score of 9 or higher were determined as PE patients. RESULTS: After treatment, the IPSS score significantly decreased in both groups. There was no statistically significant change in the PEDT for the LUTS group, but there was a significant decrease in PEDT (p=0.012; from 12.1+/-3.31 to 8.4+/-4.49) in the LUTS+PE group. CONCLUSIONS: Tamsulosin not only has a treatment effect for LUTS but also improves the PE of LUTS+PE patients. Therefore, further studies are needed to confirm the effects of tamsulosin on PE.

Effects of Tamsulosin on Premature Ejaculation in Men with Benign Prostatic Hyperplasia

PURPOSE: Previous studies have revealed that tamsulosin is effective in improving lower urinary tract symptoms (LUTS) and erectile functioning but has some inhibitory effects on ejaculation, including decreased ejaculatory volume. However, these inhibitory effects on ejaculation can be beneficial to patients with premature ejaculation (PE). Therefore, this study was conducted to understand the effect of tamsulosin on PE in men with benign prostatic hyperplasia. MATERIALS AND METHODS: Twenty-nine patients who visited with LUTS were categorized into 2 groups of LUTS-only patients (n=12) and LUTS combined with PE (LUTS+PE) patients (n=17), and 0.4 mg of tamsulosin was administered to the patients of both groups for 12 weeks. Comparative analyses of before and after the treatment were conducted for calculating the International Prostate Symptom Score (IPSS), International Index of Erectile Function-5 (IIEF-5), intravaginal ejaculatory latency time (IELT), premature ejaculation diagnostic tool (PEDT), and premature ejaculation profile (PEP). The patients with an IPSS score of 8 or higher were determined as LUTS patients, and the patients with IELT of less than 2 minutess and a PEDT score of 9 or higher were determined as PE patients. RESULTS: After treatment, the IPSS score significantly decreased in both groups. There was no statistically significant change in the PEDT for the LUTS group, but there was a significant decrease in PEDT (p=0.012; from 12.1+/-3.31 to 8.4+/-4.49) in the LUTS+PE group. CONCLUSIONS: Tamsulosin not only has a treatment effect for LUTS but also improves the PE of LUTS+PE patients. Therefore, further studies are needed to confirm the effects of tamsulosin on PE.

A Case of Wilms' Tumor Arising in Horseshoe Kidney / 대한비뇨기과학회지

Wilms' tumor is the most common renal malignancy in childhood. However Wilms' tumor originating in horseshoe kidney is rare. We present a case of Wilms' tumor arising from the isthmus of horseshoe kidney, and aim to highlight the problems faced in the diagnosis and management.

The Effect of Dialysis on Serum Prostate Specific Antigen Levels in Patients with Chronic Renal Failure / 대한비뇨기과학회지

PURPOSE: Serum levels of prostate specific antigen (PSA) have assumed a prominent clinical role in the management of prostate cancer. The aim of this study was first to determine the serum levels of total PSA, free PSA and free-to-total PSA ratio in patients with chronic renal failure, and second to investigate whether a significant difference between serum PSA levels before and after hemodialysis exists. MATERIALS AND METHODS: Serum concentrations of total PSA and free PSA were measured in 37 men with renal failure before and after hemodialysis and in 17 men with renal failure on continuous ambulatory peritoneal dialysis (CAPD). A Immuno radiometric assay was used to determine the PSA levels. RESULTS: The concentrations of total PSA were 0.83 +/- 0.54ng/ml on predialysis, 0.86 +/- 0.60ng/ml on postdialysis in hemodialysis patients and 0.71 +/- 0.29ng/ml in CAPD patients. The concentrations of free PSA were 0.35 +/- 0.21ng/ml on predialysis, 0.34 +/- 0.22ng/ml on postdialysis in hemodialysis patients and 0.37 +/- 0.11ng/ml in CAPD patients. There was no statistical differences in serum PSA between before and after hemodialysis. Free-to-total PSA ratio also showed no statistical difference. CONCLUSIONS: The limited kidney reserve in patients with chronic renal failure is sufficient to maintain the levels of total and free PSA within normal range and hemodialysis does not alter the serum level of different PSA forms. PSA measurements in patients with chronic renal failure treated by dialysis remain a useful marker of prostatic disease.

A case of Torsion of the Undescended Testis in the Infant / 대한비뇨기과학회지

No abstract available.

Renal Epidermal Growth Factor Expression and Regulation by Angiotensin II During Neonatal Ureteral Obstruction in the Rat / 대한비뇨기과학회지

No abstract available.

Vesicoureteral Reflux Secondary to a Simple Diverticulectomy: A Case Report / 대한비뇨기과학회지

A case of congenital periureteral bladder diverticulum is described. Bladder outflow obstruction and urinary tract infection were the presenting symptoms of a 2 year old boy. There were two diverticula in the bladder. The one was small (1 x 2cm) and located just above the right ureteral orifice and the other was large (8 x 10cm) and located at the left trigone. There was no hydronephrosis, and vesicoureteral reflux, neither. A simple diverticulectomy was performed. The left ureteral orifice was found at the medial side of the diverticulum's neck during operation. During follow up, bilateral high grade vesicoureteral reflux were discovered and urinary tract infections developed frequently. Eventually, ureteral reimplantation was done one year after the diverticulectomy.

Correlation between Age, Prostatic Volume and Voiding Symptoms in Randomly Selected Korean over Age 60 / 대한비뇨기과학회지

Until now, we do not have specific Korean data on the age related prostatic volume and voiding symptoms associated with prostatic volume among randomized aged population. Due to this problem, we studied the correlations on the age, prostatic volume and voiding symptom among random sampled 255 people over the age 60 from the 11 Myun in Chinyang Gun, Kyungsangnam-do from the July 12th to July 26th, 1993. The mean age of the examined people was 71.5 years. 244 people answered on questionaire for voiding symptom scoring and 224 people agreed on the transrectal ultrasonic measurement of the prostatic volume. The prolate spheroid method and elliptical method were used for the measurement of the prostatic volume with the major transverse diameter, major anteroposterior diameter and cephalocaudal diameter of each prostates as Terris. The volume of the prostate ranged from 6.2cc to 54.5cc ( Prolate spheroid method ) and 4.7cc to 44.1cc(Elliptical method ). The prostate volumes measured by the elliptical method were smaller than that measured by prolate spheroid method in each age group. The average prostatic volume measured by the elliptical volume and prolate spheroid method were 17.7/22.5cc(E/P) in age 61 to 65 group(n=17), 19.9/22.8cc in age 66 to 70 group(n= 88), 21.6/ 26.0cc in age 71 to 75 group(n=71), 24.4/27.7cc in age 76 to 80 group(n=34) and 18.1/23.7cc in age over 80 group(n =14) and the pattern of the changes in the prostatic volume related with aging was significant(p 0.05).