RESUMO
Back ground: Pre-eclampsia, is a leading cause of maternal and perinatal morbidity and mortality world-wide. Pre eclampsia accounts for majority of referrals in tertiary care center. Objective: To study the maternal and perinatal outcome in patients with severe pre eclampsia Materials and methods: This was a prospective study conducted in the Government Victoria Hospital, Andhra Medical College, Visakhapatnam from May 2018 - April 2019. Total 120 women with severe pre eclampsia after 34 weeks of gestation were included. Women with medical complication like anemia, pre-existing hypertension, epilepsy, diabetes, vascular or renal cause, multiple gestations were excluded. Patients were managed as per existing protocol after proper history, examination and investigations. Magnesium sulphate was the drug of choice for controlling convulsions and blood pressure was controlled either by labetalol or oral nefidipine. Results: Out of 120 cases of severe pre eclampsia, majority (70%) were in the age group 20-30 years and 79.16% primigravida. Edema (80.8%) was the most common presenting feature followed by headache (40.8%) in present study. 56.6% of severe pre eclampsia women were delivered vaginally and about 43.5% delivered by caesarean section, majority in view of failed induction or non-progress of labour .Maternal complication like PPH in 5.8%, eclampsia in 9.1%, acute renal failure in 0.83%, HELLP syndrome in 0.83%, pulmonary edema in 1.66%, and maternal deaths were seen in 1.66% of patients with severe pre eclampsia. In our study low birth weight was seen in 80% cases, fetal growth restriction in 20% and intra uterine fetal demise in 5% in patients with severe pre eclampsia and perinatal mortality seen in 12% cases. Conclusion: Maternal and perinatal complications are more in severe pre eclampsia and eclampsia patients. Good antenatal care, early diagnosis and prompt treatment can prevent severe pre eclampsia and eclampsia