Investigation of changes in levels of liver trans-aminases in measles affected patients hospitalized in Be'sat hospital in 1379

One of measles manifestations -especially in adolescents- is liver malfunction which can vary from just changes in liver enzymes to hepatitis with prominent jaundice. It is important to screen hepatitis patients in order to special medical treatment and avoidance of prescribing hapatotoxic drugs and some pain relief medications. In addition, patients of such complications are high risk for long duration of hospitalization and secondary complications and long duration of the disease. This was a cross-sectional study of 172 patients selected from 180 patients with clinical measles admitted in Be'sat hospital of NAHAJA. CBC and liver enzymes were checked. Patients aged between 18 to 24 years. Mean of hospitalization time was 6.48 +/- 2.37days and ranged from 2 to 14. Mean of white blood count was 4153.85 +/- 1706.08 and ranged from 1700 to 13000. PMNs percentage was 61.01 +/- 16.27 in mean and ranged from 26% to 89%. Mean of total PMN count was 2591.38 +/- 1409.42 [from 513 to 10270]. ALT [SGPT] was 40.86 +/- 33.68 in mean [from 10 to 280]. Mean of AST [SGOT] was 53.23+7- 35.76 ranged from 15 to 250. Total bilirobin was 0.9 +/- 0.31 [from 0.2 to 2.1] in mean. Mean of direct bilirobin was 0.2 +/- 0.8 ranged from 0.1 to 0.8. ALKP was 195.19+7-88.6 [from 41 to 590]. 9.5%of patients [16 patients] had liver malfunction [2 times increase of enzymes levels]. No one had jaundice at the time of admit. Comparison of evaluation of lab values of the patients with duration of hospitalization with Pearson test, only in two cases PMN percentage and total PMN had significant relation [P<0.05]. When measles patients had no complications such as secondary bacterial infections and had no history of hepatotoxic drugs, increase in liver enzymes levels is mild and had no significant clinical interest

[Evaluation of Factors related death prognosis in hospitalized Tuberculosis patients]

Backgroud: tuberculosis is one of the oldest Known diseases with high annual rates of mortality and morbidity around the globe. A better understanding of factors relating to death prognosis in tuberculosis Patients enhances treatment strategies. this study was conducted for the mentioned purpose

Materials and Methods: in this case-control study, all cases and controls where matched by age and sex and selected from patients with a definit or suspected diagnosis of tuberculosis hospitalized in the Massih Daneshvari Hospital, during the year 2002. Data were analyzed using non parametric Measures for qualitative variables, X[2][for qualitative variables [CI,OR], and logestic Regression using wald method

Results: 33 cases were enrolled call passed away; 11 [33%] were female and the rest were male [53þ +/- 16/5]. Half of the deaths occurred in the first six days of hospitalization. 50% of the cases were smokers. 3 [9%] were HIV Positive. In the control group [all alive], Significant differences were found with regard to smoking [P=0.003], PMN count [P=0.001]

Conclusions: this study suggested that smoking is an important risk factor for mortality in tuberculosis. Smoker TB Patients died 5.6 frequently than non-Smoker. Lymphocytopenic patients had poor prognosis in comparison with normal Lymphocyte counts

[Investigation of changes in levels of liver trans-aminases in measles affected patients hospitalized in Be'sat hospital in 1379]

Background: One of measles manifestations -especially in adolescents- is liver malfunction which can vary from just changes in liver enzymes to hepatitis with prominent jaundice. It is important to screen hepatitis patients in order to special medical treatment and avoidance of prescribing hapatotoxic drugs and some pain relief medications. In addition, patients of such complications are high risk for long duration of hospitalization and secondary complications and long duration of the disease

Materials and methods: This was a cross-sectional study of 172 patients selected from 180 patients with clinical measles admitted in Be'sat hospital of NAHAJA. CBC and liver enzymes were checked

Results: Patients aged between 18 to 24 years. Mean of hospitalization time was 6.48 +/- 2.37days and ranged from 2 to 14. Mean of white blood count was 4153.85 +/-1706.08 and ranged from 1700 to 13000. PMNs percentage was 61.01+/-16.27 in mean and ranged from 26% to 89%. Mean of total PMN count was 2591.38+/-1409.42 [from 513 to 10270]. ALT [SGPT] was 40.86+/-33.68 in mean [from 10 to 280]. Mean of AST [SGOT] was 53.23+/- 35.76 ranged from 15 to 250. Total bilirobin was 0.9+/-0.31 [from 0.2 to 2.1] in mean. Mean of direct bilirobin was 0.2+/-0.8 ranged from 0.1 to 0.8. ALKP was 195.19+/-88.6 [from 41 to 590]. 9.5 %of patients [16 patients] had liver malfunction [2 times increase of enzymes levels]. No one had jaundice at the time of admit. Comparison of evaluation of lab values of the patients with duration of hospitalization with Pearson test, only in two cases PMN percentage and total PMN had significant relation [P<0.05]

Conclusions: When measles patients had no complications such as secondary bacterial infections and had no history of hepatotoxic drugs, increase in liver enzymes levels is mild and had no significant clinical interest