RESUMO
Objective: comparison of intraocular pressure alternations measured by Schiotz tonometry before and after induction of anesthezia by ketamine and acepromazine in stray cats. The effects of factors like age, sex and iris color on intraocular pressure were also studied
Design: uncontrolled clinical trial
Animals: hundred stray cats were used in the study
Material and methods: hundred stray cats were collected from different portions of Tehran by a special cage designed to do this. To improve the accuracy of data in each case measurement was performed three times and it's average was recorded as IOP in that animal. Furthermore, because in many clinical examinations especially when the animal suffer from pain due to glaucoma use of anesthesia is obligatory and to assess the effect of anesthesia on IOP, all of the cats were anesthetized by ketamine hydrochloride and acepromazine in traditional doses and IOPs were measured again in this situation
Statistical analysis: in this study statistical analysis were performed by independent t test, paired t test, one way ANOVA and tookey as complementary test
Results: in this study, the mean of IOP was 17.5 +/- 0.46 mmHg. Furthermore, the results of this study showed that sex and color of iris had no significant effect in IOP, but in respect to age based on statistical ANOVA test, the difference was significant. Younger animals had higher values of IOP compared with older cats. Beside this, the results of this study showed that anesthesia with ketamine and acepromazine in cats can lead to increase in IOP and x =[y-0.743/1.021] formula, as an index, can be used for IOP determination in situations that anesthesia performance is obligatory [x = corrected IOP value before anesthesia induction, y = acquired IOP value after anesthesia]
Discussion: from the factors evaluated in this study, just age had a significant influence on IOP. Beside this for determination of glaucoma especially when use of ketamine and acepromazine are obligatory and there is considerable pain in the patient and physical restraint is impossible, this could lead in increase of IOP in affected animals. To evaluate IOP properly in this conditions use of correction coefficients could be helpful