Pelvic endometriosis a Rare Cause of massive hemorrhagic Ascites

Endometriosis is defined as the presence of endometrial tissue outside the uterine cavity. It generally involves the peritoneum, ovaries and rectovaginal septum. Recurrent hemorrhagic ascites secondary to endometriosis is an unusual occurrence, 42 cases have been reported worldwide since 1954. It is more commonly seen in black nulliparous females. We report a case to draw attention to this condition as a potential cause for massive hemorrhagic ascites

Evaluation of doppler indices of maternal uterine artery in cases with early idiopathic recurrent abortion

This study was performed on 120 pregnant women at early pregnancy. They were divided into two groups: The control group [I] included 30 normal pregnant women with no history of abortion and the study group [II] included 90 pregnant women with history of two or more unexplained abortion who were further subdivided randomly into three subgroups. All patients in the subgroups were given folic acid and low-dose aspirin; they were given alone to patients in group IIa, patients in group IIb received also nitroglycerine 5 TTS skin patches [5 mg each] and patients in group IIc were given 1.2 MIU of long- acting penicillin every two weeks. Doppler study of the uterine artery blood flow was performed at the time of vaginal ultrasound examination at different intervals of gestational age for all patients in all groups. A follow up of pregnancy was done every 2 weeks till 20 weeks [age of viability] or abortion occurred. The study concluded that uterine artery Doppler indices [resistivity index, RI, and pulsatility index, PI] significantly decreased with the increasing gestational age. Treatment with folic acid, pediatric aspirin, nitroglycerine patches and long-acting penicillin resulted in Doppler indices close to the control group results and in a better pregnancy outcome

comparative study on the effect of PGE1 and PGE2 on the pregnant uterus of mice

Using the pregnant uterus of mice, the effect of dinoprostone [PG E2] and misoprostol [PG E1] on uterine activity was compared. Both PG E1 and PG E2 were able to increase the uterine resting tone and amplitude of contractions. However, PG E1 caused magnification of the normal configuration of the wave of uterine contraction together with moderate increase of resting tone, while PG E2 caused initially a sharp increase in the tone with a sustained contraction showing only minimal oscillations. Both PG E1 and PG E2 were found to be effective in stimulating uterine activity. At the same time, PG E1 did induce a more physiological type of contraction that may be safer for labor induction than that produced by PG E2. Furthermore, the effect of both drugs was antagonized by the beta 2 sympathomimetric albuterol. The results indicated that beta 2 agonists could be used to stop uterine hypertonicity or to postpone uterine activity till the cervix is sufficiently ripened to minimize the effect of these contractions on both mother and fetus