Association of HLA-B27 with ankylosing spondylitis in Isfahan, Iran

Using a standard microcytotoxicity [NIH] technique of tissue typing, the HLA-B27 antigen was identified in 30 out of 34 patients [88.2%] with classical ankylosing spondylitis [AS], compared to 6 out of 70 controls [8.6%] [P < 0.005]. We also found this antigen in 8 out of 76 [10.5%] patients with non-AS arthritis