RESUMO
The objective of this study is that, obese Saudi groups are prone to atherosclerosis more than non-obese due to lower level of serum paraoxonase activity. Patients and Sixty-two [62] subjects; 37 obese [19 males, 18 females] and 25 control groups [non-obese] [13 males, 12 females] at King Abdulaziz University Hospital, Jeddah, KSA - age range of 29 - 68 years. All obese groups have their body mass index [BMI] above 30. For both groups' complete medical examination was done, total cholesterol, triglycerides, LDL and HDL cholesterol, C-reactive protein and serum paraoxonase level was measured. Results showed that there was a significant difference in serum paraoxonase level, being much higher in non-obese groups compared to lower serum paraoxonase level in obese groups [p<0.05]. Serum paraoxonase is a marker of increasing susceptibility of the obese groups to atherosclerosis