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1.
LJM-Libyan Journal of Medicine. 2009; 4 (3): 104-106
em Inglês | IMEMR | ID: emr-146589

RESUMO

Clindamycin has been used successfully to treat pneumonia and soft-tissue infections caused by methicillin-resistant Staphylococcus aureus. However, inducible clindamycin resistance has been described as a cause of treatment failure of such infections. A total of 159 staphylococcal isolates from different clinical specimens from burn patients in Tripoli Burn Center were tested for inducible clindamycin resistance by the disk-diffusion induction test. Inducible clindamycin resistance was detected in 66.2% of 65 methicillin-resistant S. aureus isolates and in none of 55 methicillin-sensitive S. aureus, 10 methicillin-resistant coagulase negative staphylococci and 29 methicllin-sensitive coagulase negative staphylococci isolates. In our setting, clindamycin can be used for the treatment of infections due to staphylococci, but we recommend that staphylococci isolates, particularly methicillin-resistant S. aureus, are tested by the D-test before treatment


Assuntos
Clindamicina/farmacologia , Farmacorresistência Bacteriana , Infecções Estafilocócicas/tratamento farmacológico , Staphylococcus/efeitos dos fármacos , Staphylococcus aureus/isolamento & purificação , Testes de Sensibilidade Microbiana , Queimaduras/microbiologia , /farmacologia , Infecção Hospitalar
2.
Archives de l'Institut Pasteur de Tunis. 1995; 72 (1-2): 13-15
em Francês | IMEMR | ID: emr-36442

RESUMO

Twenty seven Aeromonas strains [5A, hydrophila, 8A. sobria and 14A. caviae] isolated from children with diarrhoea and 34 Aeromonas strains [9A. hydrophila. 7A. sobria and 18A. caviae] isolated from children without diarrhoea were tested from haemolysin production. The results obtained showed that haemolysin production using human, horse or sheep erythrocytes was significantly associated with A. hydrophila and A. sobria but not with A. caviae, regardless of whether these strains were isolated from children with or without diarrhoea. Human or horse rather than sheep erythrocytes are recommended for use in the haemolysin assay


Assuntos
Humanos , Aeromonas/imunologia , Proteínas Hemolisinas , Diarreia
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