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Journal of Medical Council of Islamic Republic of Iran. 2005; 22 (4): 338-342
em Persa | IMEMR | ID: emr-72073

RESUMO

The major underlying pathology in chronic granulomatous disease is a primary defect in membranous oxidase of phagocytic cells. Affected patients suffer from recurrent cutaneous and visceral abscess formation by catalase positive micro-organisms. The other characteristic features of the disease are granulomas in gastrointestinal, respiratory and urinary tracts. In this study we review the natural course of the disease in a 12 year old boy. He had a violaceous chronic granuloma on his nose since 7 yr of age. Recently the redness of his eyes and photophobia has been worsened. An ophthalmologic consultaion confirmed a chronic keratitis, and ultimately immunological and bacteriological tests coupled with a pathology specimen documented the diagnosis of chronic granulomatosis. With appropriate treatment, the clinical symptomatology of the child improved


Assuntos
Humanos , Masculino , Doença Granulomatosa Crônica/diagnóstico , Manifestações Oculares , Fotofobia , Ceratite
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