RESUMO
<p><b>OBJECTIVE</b>To evaluate the effect the vaccine of hemorrhagic fever with renal syndrome (HFRS).</p><p><b>METHODS</b>Data of totally, 1095 individuals who were immunized with HFRS vaccine type produced by Shenyang Baiao Biotechnology, Ltd were analyzed. 1999-2000 in Laiwu City.</p><p><b>RESULTS</b>Most of the individuals belonged to rural population. In most cases the vaccination was done in spring and autumn. Persons between ages 18-40 years dominated the series. The side effects of the vaccination were seen in 1.71% in which local reaction was 1.35%, general reaction 0.30%, abnormal reaction 0.06% and the lowest reaction rate was seen in the group between ages 7-17.</p><p><b>CONCLUSIONS</b>The vaccine was quite effective. Both antibody positive ratio and GMT level of antibody were high.</p>