C-peptide and glycaemic state in obese and non-obese type II diabetes

This study was carried out on 60 obese patients with type II diabetes and 57 non-obese patients with type II diabetes. Estimation of body mass index was significantly higher in group I [31. +/- 3.3 kg/m[2]] than in group II [22.8 +/- 3 kg/m[2]]. Studying of the glycaemic state in both groups by measuring fasting blood glucose and glycosylated hemoglobin did not reveal any significant changes. While estimation of plasma C-peptide level showed significantly higher level in group I [3.37 +/- 1.5 ng/ml] than in group II [2.25. +/- 1.3 ng/ml]. This increase in plasma C-peptide in group 1 is explained by the presence of insulin resistance in obese patients. Discussion of etiology of these results is mentioned