Chondroid lipoma of breast: a rare pathology

Chondroid lipoma, is an uncommon benign breast neoplasm. We report a case of Chondroid lipoma in a 57 years old lady presenting with 01 year history of breast lump

Breast Pseudoangiomatous Stromal Hyperplasia challenges

Pseudoangiomatous stromal hyperplasia [PASH] is a rare proliferative breast disease. It is characterized by fibrosis of the mammary stroma surrounding breast ducts and lobules with formation of anatomizing capillary-like spaces lined by myofibroblastic cells. Commonly, patients present with a palpable breast mass or continuous breast enlargement. We report a case of a 25 year old lady who presented with painless unilateral swelling of her right breast. Ultrasonography showed heterogeneous, hypoechoic benign appearing breast tissue. Histopathology revealed dense collagenous stroma separated by slit like spaces that were lined by bland spindle cells showing no cytological atypia. With immunohistochemistry, these cells were positive for CD-34 and SMA and negative for the endothelial marker CD-31. Some of these cells were also positive for ER and PR.

Tuberculosis of the breast

A study was conducted to find out the frequency of breast tuberculosis and its treatment outcome, at the breast clinic of surgical unit 1 ward 3 JPMC Karachi. The study comprised of 152 patients of breast lumps between March 2000 and September 2001, out of which 35 showed positive FNAC for tuberculosis [23%]. They responded very well to antituberculosis chemotherapy and the lump totally disappeared within 12 months of therapy. Hence early diagnosis, before sinuses develop is important in preventing disfigurenment