RESUMO
OBJECTIVE: To determine the frequency of Malnutrition Inflammation Complex Syndrome [MICS] in patients with End Stage kidney disease on maintenance hemodialysis patients presenting to tertiary care Hospital in Karachi
DESIGN: A cross sectional study
SETTINGS: Department of Nephrology Jinnah Postgraduate Medical Center, Karachi
METHODS: Total of 62 patients was included through non-probability purposive sampling
All patients diagnosed with End stage kidney disease on maintenance hemodialysis [twice week for >3months] were included and patients with acute kidney injury, chronic infections and chronic liver disease were excluded. Malnutrition inflammation score [MIS] was used to determine malnutrition inflammation complex syndrome [MICS]. Mean and standard deviation were calculated for continuous variables, and percentages or proportions for categorical variables
Chi square test was used to determine the proportion of MICS in Maintenance Hemodialysis patients
RESULTS: Mean age was 46 years +/-12.59 SD [range 18-72 years]. 34 [55%] were females and 28 [45%] males. 26 [42%] patients had duration of Maintenance Hemodialysis<1 years and 28[45%] between 1-4 years. Frequency of malnutrition complex syndrome [MICS] in patients with end stage renal failure was noted in 60 [97%] patients, out of these 31[50%] patients had mild MICS and 29 [47%] patients moderate MICS. Mild and Moderate malnutrition complex syndrome [MICS] was more observed in age group of 31-40years [12% in mild and 14% in moderate [MCIS].Moderate MICS was higher in females and mild MICS was higher in male patients
CONCLUSION: Our study concluded that most [97%] of our patients with end stage kidney disease on maintenance hemodialysis has evidence of malnutrition inflammation complex syndrome