Effect of praziquantel on sex hormone level in murine schistosomiasis mansoni

Changes in sex hormonal levels were studied in Schistosoma mansoni infected and praziquantel treated mice [400 x 2 mg/kg], drug control and in normal control groups. It was observed that schistosomiasis lead to increase in the level of testosterone, progesterone and 17 beta-estradiol, 60 and 70 days post-infection in male and female mice, respectively. In praziquantel treated group the level of testosterone was lowered 10, 20 and 30 days post-treatment, progesterone and 17 beta-estradiol fell 30 days post treatment after primary rise. The mechanism of recorded changes was discussed in details

Congenital toxoplasmosis among premature infants with different clinical pictures in Saudi Arabia

No doubt, toxoplasmosis is prevalent infection in all the Arab countries. However, the incidence differs from one country to another and even within the same country. Congenital toxoplasmosis is the most important form of the infection. In the present study, some 78 premature infants with different clinical pictures were examined for toxoplasma IgG [by IHAT and ELISA] and toxoplasma IgM [by ELISA]. The results showed toxoplasma IgG ranging between 32.1% [IHAT] and 46.2% [ELISA], while IgM [ELISA] was 23.1%. The highest positivity rate was among suffering jaundice and the lowest was among those suffering fever of unknown origin. Protection of women, particularly pregnant ones, from toxoplasma infection is must

clinical picture of six Egyptian cases of cutaneous leishmaniasis

Cutaneous leishmaniasis [CL] is a skin disease encountered in the East Mediterranean Region including Egypt. In this paper, it was intended to throw some light on the clinical picture of six parasitologically proven human CL. The results of treating three cases of them with Pentostam or Cryosurgery were given. The whole results were discussed