RESUMO
Chronic obstructive pulmonary disease (COPD) is a group of symptoms, which defined as persistent airflow limitation due to alveolar and airway abnormality which caused by chronic inflammation of airway and lung parenchyma. It is stated that it has leading cause of mortality and morbidity. It is projected to rank third among all causes of death by 2020. It has complex pathology with marked heterogeneity all over India. Now days it is markedly increasing in India due to biomass, occupational and household exposures. COPD leads to variety of intra and extra-pulmonary component and considerable effect of public health incidence are increasing in India mainly Uttar Pradesh and Bihar due to increase dependence to biomass and conventional exposure to noxious agents (Smoke, Biomass fuel, Dust particles).