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Indian J Exp Biol ; 2006 Mar; 44(3): 228-32
Artigo em Inglês | IMSEAR | ID: sea-60897

RESUMO

Histopathological changes were observed in liver, kidney and muscles of normal, protein-malnourished, diabetic as well as both protein-malnourished and diabetic albino rats when exposed to a mixture of monocrotophos, hexachlorocyclohexane and endosulfan at varying intervals. The examination revealed hepatotoxic, nephrotoxic and muscular necrotic effects in pesticides exposed rats. Toxicity was aggravated in protein-malnourished and diabetic animals and more so, if the animals were both diabetic and protein-malnourished.


Assuntos
Animais , Diabetes Mellitus/patologia , Endossulfano/farmacologia , Feminino , Rim/efeitos dos fármacos , Hexaclorocicloexano/farmacologia , Fígado/efeitos dos fármacos , Masculino , Desnutrição/patologia , Monocrotofós/farmacologia , Músculos/efeitos dos fármacos , Praguicidas/farmacologia , Ratos , Ratos Wistar
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