Methicillin-Resistant Staphylococcus aureus (MRSA) Colonization, Risk Factors, and Antibiotic Susceptibility Profile Among Asymptomatic Diabetes Mellitus Type 2 Patients

@#BACKGROUND: Methicillin-resistant Staphylococcus aureus (MRSA) related infections are increased in patients with Diabetes Mellitus and are associated with increased morbidity and mortality. OBJECTIVES: This study aims to determine the prevalence, risk factors, and antimicrobial susceptibility patterns of MRSA nasal colonization among individuals with diabetes mellitus. METHODOLOGY: This is a prospective cross-sectional study that included adult Filipino patients with diabetes mellitus type 2. Nasal swab samples were analyzed for the presence of MRSA. RESULTS: MRSA nasal colonization has a prevalence rate of 6.8% which was associated with a history of antibiotic use. The isolates exhibited resistance to Benzypenicillin/Oxacillin (100%), Clindamycin (42.9%), Vancomycin, and Trimethoprim/Sulfamethoxazole (14.3%). CONCLUSION: The prevalence of MRSA in this population is higher compared with other Asian countries. No diabetic-related risk factors were identified to be associated with MRSA nasal colonization. The presence of resistance to most commonly used antibiotics should prompt clinicians appropriately treat infections caused by this organism.

A trial of Oral Glucocorticoids in the resolution of recurrent Granulomatous Hypophysitis: A case report / Journal of the ASEAN Federation of Endocrine Societies

@#Granulomatous hypophysitis is an extremely rare condition, with no established definitive treatment. An elderly Asian woman was diagnosed to have recurrent granulomatous hypophysitis 5 years after transsphenoidal surgery. No other intervention was done post-operatively. Since another surgery was not advisable due to the high probability of recurrence, she was started on a trial of oral glucocorticoids. After 3 months of steroid therapy, complete resolution of symptoms and sellar mass were achieved.

Prevalence of sexual dysfunction and its associated factors among women with Diabetes Mellitus Type 2 at Makati Medical Center Outpatient Department / Journal of the ASEAN Federation of Endocrine Societies

Objective@#This study aims to determine the prevalence of sexual dysfunction among premenopausal Filipino women with type 2 diabetes mellitus at the outpatient department of a tertiary hospital through the use of the Female Sexual Function Index (FSFI) and identify factors that could be associated with sexual dysfunction.@*Methodology@#Seventy-five women with type 2 diabetes mellitus, aged 38 to 49 years old, received the FSFI questionnaire. Their age, history of hypertension, smoking habit, alcohol intake, body mass index, waist circumference, fasting blood sugar, HbA1c, creatinine, lipid profile, albuminuria or proteinuria, presence of microvascular complications such as diabetic retinopathy, neuropathy and nephropathy and their association with sexual dysfunction was determined.@*Results@#Seventy-two percent of the participants have sexual dysfunction scoring lowest in the lubrication, orgasm and pain domains. Age (p=0.016), a high body mass index (p=0.001), a fasting blood sugar above 100 mg/dl (p=0.006) and the presence of microvascular complications of diabetes mellitus namely, retinopathy (p=0.046) nephropathy (p=0.004) and neuropathy (p=0.001) were associated with sexual dysfunction.@*Conclusion@#The prevalence of sexual dysfunction is high among premenopausal Filipino women with type 2 diabetes mellitus, and is associated with age, a high body mass index, an uncontrolled fasting blood sugar and the presence of microvascular complications of diabetes mellitus.