1.
Acta Pharmaceutica Sinica
;
(12): 180-183, 2004.
Artigo
em Chinês
| WPRIM
| ID: wpr-301119
RESUMO
<p><b>AIM</b>To provide basic data for the synthesis of new sinomenine derivatives.</p><p><b>METHODS</b>The C ring in sinomenine was modified.</p><p><b>RESULTS</b>Seven compounds were prepared and screened for anti-inflammatory and analgesic activities. Compounds 2 and 5 showed better activities.</p><p><b>CONCLUSION</b>Modification of the C ring in sinomenine should be worthy to be studied further.</p>