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Objective To observe the therapeutic effect on the treatment of avascular necrosis of femoral head by core decompression with autograft of mesenchymal stem cells(MSCs).Methods Nineteen patients with avascular necrosis of femoral head,including 8 cases of phase I,6 cases of phase II and 5 cases of phase III based on ARCO classification,were treated with core decompression with autograft of MSCs.Results The patients were followed up for one year.The average ratio of necrosis zone diminished from 31.88% to 13.18%.The Harris hip score was increased significantly.Conclusion The treatment of core decompression with autograft of MSCs is safe and effective,and it deserves to application in early necrosis of femoral head.
RESUMO
Objective: To study the related factors of artery occlusion induced cardiac infarction. Methods: The coronary angiography data of 56 patients with total artery occlusion were retrospectively studied. The patients were divided into 2 groups: Group A with cardiac infarction, Group B without cardiac infarction, and the clinical features of the 2 groups were compared. Results: It was found that diabetes mellitus, anginal pectoris, hypercholesterolemia, high and low density lipoprotein, smoking, long term medication, collateral circulation, and changes of electrocardiogram presentation were all related factors of infarction( P 6 months), long term medication, well controlled blood glucose and lipoprotein, and non smoking, probably because these factors can improve the collateral circulation and induce ischemia preconditioning.