1.
Journal of International Oncology
; (12): 169-171,233, 2012.
Artigo
em Chinês
| WPRIM
| ID: wpr-597892
RESUMO
Aminopeptidase N,a zinc-dependent exopeptidase,is highly expressed in many kinds of tumors,which involves in the degradation of extracellular matrix barriers and angiogenesis and promotes the invasion and metastasis of cancer cells.Aminopeptidase N inhibitors can induce apoptosis and inhibit the invasion and metastasis of tumor cells,which has become an attractive target for anti-tumor therapy.